A Molecular Mechanism Study to Reveal Hirudin's Downregulation to PI3K/AKT Signaling Pathway through Decreasing PDGFR<i>ß</i> in Renal Fibrosis Treatment.

Li, Ying; Zhang, Ling; Xiong, Weijian; Gao, Xuan; Xiong, Yanying; Sun, Wei

A Molecular Mechanism Study to Reveal Hirudin's Downregulation to PI3K/AKT Signaling Pathway through Decreasing PDGFRß in Renal Fibrosis Treatment.

Li, Ying; Zhang, Ling; Xiong, Weijian; Gao, Xuan; Xiong, Yanying; Sun, Wei.

Li Y; Nanjing University of Chinese Medicine, Nanjing 210023, China.
Zhang L; Department of Nephrology, Chongqing Hospital of Traditional Chinese Medicine, Chongqing 400021, China.
Xiong W; Department of Nephrology, Chongqing Hospital of Traditional Chinese Medicine, Chongqing 400021, China.
Gao X; Department of Nephrology, Chongqing Hospital of Traditional Chinese Medicine, Chongqing 400021, China.
Xiong Y; Department of Nephrology, Chongqing Hospital of Traditional Chinese Medicine, Chongqing 400021, China.
Sun W; Nanjing University of Chinese Medicine, Nanjing 210023, China.

Biomed Res Int ; 2022: 5481552, 2022.

Article en En | MEDLINE | ID: mdl-36119923

Asunto(s)

Enfermedades Renales; Proteínas Proto-Oncogénicas c-akt; Animales; Cadherinas/metabolismo; Regulación hacia Abajo; Transición Epitelial-Mesenquimal; Fibronectinas/metabolismo; Fibrosis; Hirudinas/farmacología; Enfermedades Renales/metabolismo; Fosfatidilinositol 3-Quinasas/metabolismo; Proteínas Proto-Oncogénicas c-akt/metabolismo; Transducción de Señal; Factor de Crecimiento Transformador beta/metabolismo; Vimentina/metabolismo

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas Proto-Oncogénicas c-akt / Enfermedades Renales Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Año: 2022 Tipo del documento: Article

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