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A humanized minipig model for the toxicological testing of therapeutic recombinant antibodies.
Flisikowska, Tatiana; Egli, Jerome; Flisikowski, Krzysztof; Stumbaum, Marlene; Küng, Erich; Ebeling, Martin; Schmucki, Roland; Georges, Guy; Singer, Thomas; Kurome, Mayuko; Kessler, Barbara; Zakhartchenko, Valeri; Wolf, Eckhard; Weber, Felix; Schnieke, Angelika; Iglesias, Antonio.
  • Flisikowska T; Department of Molecular Life Sciences, Chair of Livestock Biotechnology, School of Life Sciences Weihenstephan, Technical University München, Freising, Germany.
  • Egli J; Roche Pharmaceutical Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland.
  • Flisikowski K; Department of Molecular Life Sciences, Chair of Livestock Biotechnology, School of Life Sciences Weihenstephan, Technical University München, Freising, Germany.
  • Stumbaum M; Department of Molecular Life Sciences, Chair of Livestock Biotechnology, School of Life Sciences Weihenstephan, Technical University München, Freising, Germany.
  • Küng E; Roche Pharmaceutical Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland.
  • Ebeling M; Roche Pharmaceutical Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland.
  • Schmucki R; Roche Pharmaceutical Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland.
  • Georges G; Roche Pharmaceutical Research and Early Development, Roche Innovation Center Munich, Penzberg, Germany.
  • Singer T; Roche Pharmaceutical Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland.
  • Kurome M; Gene Center and Department of Veterinary Sciences, Molecular Animal Breeding and Biotechnology, Ludwig-Maximilians-Universität München, Munich, Germany.
  • Kessler B; Gene Center and Department of Veterinary Sciences, Molecular Animal Breeding and Biotechnology, Ludwig-Maximilians-Universität München, Munich, Germany.
  • Zakhartchenko V; Gene Center and Department of Veterinary Sciences, Molecular Animal Breeding and Biotechnology, Ludwig-Maximilians-Universität München, Munich, Germany.
  • Wolf E; Gene Center and Department of Veterinary Sciences, Molecular Animal Breeding and Biotechnology, Ludwig-Maximilians-Universität München, Munich, Germany.
  • Weber F; Roche Pharmaceutical Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland. felix.weber@roche.com.
  • Schnieke A; Department of Molecular Life Sciences, Chair of Livestock Biotechnology, School of Life Sciences Weihenstephan, Technical University München, Freising, Germany. schnieke@tum.de.
  • Iglesias A; Roche Pharmaceutical Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland.
Nat Biomed Eng ; 6(11): 1248-1256, 2022 11.
Article en En | MEDLINE | ID: mdl-36138193
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Cadenas Pesadas de Inmunoglobulina Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2022 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Cadenas Pesadas de Inmunoglobulina Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2022 Tipo del documento: Article