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Aptamer-engineered extended-gate field-effect transistor device for point-of-care therapeutic drug monitoring.
Zhang, Mengyang; He, Junqing; Zheng, Youbin; Shi, Guoyue; Zhang, Min.
  • Zhang M; School of Chemistry and Molecular Engineering, Shanghai Key Laboratory for Urban Ecological Processes and Eco-Restoration, East China Normal University, Shanghai 200241, China. mzhang@chem.ecnu.edu.cn.
  • He J; School of Chemistry and Molecular Engineering, Shanghai Key Laboratory for Urban Ecological Processes and Eco-Restoration, East China Normal University, Shanghai 200241, China. mzhang@chem.ecnu.edu.cn.
  • Zheng Y; Department of Chemical Engineering, Technion - Israel Institute of Technology, Haifa 320003, Israel.
  • Shi G; School of Chemistry and Molecular Engineering, Shanghai Key Laboratory for Urban Ecological Processes and Eco-Restoration, East China Normal University, Shanghai 200241, China. mzhang@chem.ecnu.edu.cn.
  • Zhang M; School of Chemistry and Molecular Engineering, Shanghai Key Laboratory for Urban Ecological Processes and Eco-Restoration, East China Normal University, Shanghai 200241, China. mzhang@chem.ecnu.edu.cn.
Analyst ; 147(20): 4413-4416, 2022 Oct 10.
Article en En | MEDLINE | ID: mdl-36148514
Herein, we report a portable point-of-care testing (POCT) device based on an aptamer-engineered extended-gate field-effect transistor (EG-FET) for therapeutic monitoring of the drug methotrexate. This method was shown to be highly sensitive, efficient, and convenient to use, features contributing to its realizing a clinical detection of drugs in blood.
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Técnicas Biosensibles Idioma: En Año: 2022 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Técnicas Biosensibles Idioma: En Año: 2022 Tipo del documento: Article