Corneal densitometry in bilateral keratoconus patients with unilateral corneal Vogt's striae: a contralateral eye study.
Int Ophthalmol
; 43(3): 885-897, 2023 Mar.
Article
en En
| MEDLINE
| ID: mdl-36153430
ABSTRACT
PURPOSE:
To investigate corneal densitometry and correlations with corneal morphological parameters in patients with bilateral keratoconus (KC) with unilateral Vogt's striae.METHODS:
This prospective contralateral study enrolled 112 patients (224 eyes) with evident KC characteristics (corneal topography with asymmetric bow-tie pattern, inferior steepening), and at least one KC sign (conical protrusion of the cornea at the apex, corneal stromal thinning, Fleischer ring, Vogt's striae) on slit-lamp examination. Corneal densitometry and morphological parameters were measured using Pentacam HR.RESULTS:
The mean age was 23.93 ± 6.81 years. Fifty-two (23.22%), 111 (49.55%), and 61 (27.23%) eyes were in mild, moderate, and severe groups, respectively. Corneal densitometry values of the anterior 0-2 mm and 2-6 mm, intermediate 0-2 mm and 2-6 mm, posterior 2-6 mm, and total cornea 2-6 mm were significantly higher in eyes with Vogt's striae (P < 0.05), whereas those of the anterior 6-10 mm, posterior 0-2 mm, and total cornea 6-10 mm were significantly lower in eyes with Vogt's striae (P < 0.05). Anterior 0-2 mm and total cornea 2-6 mm corneal densitometry values were positively correlated with anterior K1 (A-K1), K2 (A-K2), Km (A-Km), Kmax (A-Kmax), anterior corneal elevation, and posterior corneal elevation (P < 0.05), and negatively correlated with central corneal thickness and thinnest corneal thickness in eyes with Vogt's striae (P < 0.05). A-K2, A-Km, and A-Kmax were significantly correlated with the densitometry values of the anterior 0-2 mm and intermediate 0-2 mm in eyes without Vogt's striae (P < 0.05).CONCLUSION:
Vogt's striae mainly occur on the anterior and intermediate layers during KC progression.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Queratocono
Límite:
Adolescent
/
Adult
/
Humans
Idioma:
En
Año:
2023
Tipo del documento:
Article