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Lactic acid bacteria-derived γ-linolenic acid metabolites are PPARδ ligands that reduce lipid accumulation in human intestinal organoids.
Noguchi, Makoto; Shimizu, Makoto; Lu, Peng; Takahashi, Yu; Yamauchi, Yoshio; Sato, Shintaro; Kiyono, Hiroshi; Kishino, Shigenobu; Ogawa, Jun; Nagata, Koji; Sato, Ryuichiro.
  • Noguchi M; Nutri-Life Science Laboratory, Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan.
  • Shimizu M; Nutri-Life Science Laboratory, Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan. Electronic address: amshimizu@g.ecc.u-tokyo.ac.jp.
  • Lu P; Food Biotechnology and Structural Biology Laboratory, Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan.
  • Takahashi Y; Food Biochemistry Laboratory, Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan.
  • Yamauchi Y; Nutri-Life Science Laboratory, Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan; Food Biochemistry Laboratory, Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The Univer
  • Sato S; Department of Microbiology and Immunology, School of Pharmaceutical Sciences, Wakayama Medical University, Wakayama, Japan.
  • Kiyono H; Mucosal Immunology and Allergy Therapeutics, Institute for Global Prominent Research, Future Medicine Education and Research Organization, Chiba University, Chiba, Japan.
  • Kishino S; Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Kyoto, Japan.
  • Ogawa J; Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Kyoto, Japan.
  • Nagata K; Food Biotechnology and Structural Biology Laboratory, Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan.
  • Sato R; Nutri-Life Science Laboratory, Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan. Electronic address: roysato@g.ecc.u-tokyo.ac.jp.
J Biol Chem ; 298(11): 102534, 2022 11.
Article en En | MEDLINE | ID: mdl-36162507
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Ácido gammalinolénico / PPAR delta / Lactobacillales / Intestino Delgado Límite: Humans Idioma: En Año: 2022 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Ácido gammalinolénico / PPAR delta / Lactobacillales / Intestino Delgado Límite: Humans Idioma: En Año: 2022 Tipo del documento: Article