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Time matters - in vitro cellular disposition kinetics help rationalizing cellular potency disconnects.
Poller, Birk; Werner, Sophie; Domange, Norbert; Mettler, Lina; Stein, Richard R; Loretan, Jacqueline; Wartmann, Markus; Faller, Bernard; Huth, Felix.
  • Poller B; Pharmacokinetic Sciences, Novartis Institutes for Biomedical Research, Basel, Switzerland.
  • Werner S; Pharmacokinetic Sciences, Novartis Institutes for Biomedical Research, Basel, Switzerland.
  • Domange N; Pharmacokinetic Sciences, Novartis Institutes for Biomedical Research, Basel, Switzerland.
  • Mettler L; Pharmacokinetic Sciences, Novartis Institutes for Biomedical Research, Basel, Switzerland.
  • Stein RR; Pharmacokinetic Sciences, Novartis Institutes for Biomedical Research, Basel, Switzerland.
  • Loretan J; Oncology, Novartis Institutes for Biomedical Research, Basel, Switzerland.
  • Wartmann M; Oncology, Novartis Institutes for Biomedical Research, Basel, Switzerland.
  • Faller B; Pharmacokinetic Sciences, Novartis Institutes for Biomedical Research, Basel, Switzerland.
  • Huth F; Pharmacokinetic Sciences, Novartis Institutes for Biomedical Research, Basel, Switzerland.
Xenobiotica ; 52(8): 878-889, 2022 Aug.
Article en En | MEDLINE | ID: mdl-36189672
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Descubrimiento de Drogas Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Año: 2022 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Descubrimiento de Drogas Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Año: 2022 Tipo del documento: Article