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Repurposing of the FGFR inhibitor AZD4547 as a potent inhibitor of necroptosis by selectively targeting RIPK1.
Wang, Zuo-Wei; Zou, Feng-Ming; Wang, Ao-Li; Yang, Jing; Jin, Rui; Wang, Bei-Lei; Shen, Li-Juan; Qi, Shuang; Liu, Juan; Liu, Jing; Wang, Wen-Chao; Liu, Qing-Song.
  • Wang ZW; Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, 230031, China.
  • Zou FM; University of Science and Technology of China, Hefei, 230026, China.
  • Wang AL; Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, 230031, China.
  • Yang J; Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, 230031, China.
  • Jin R; Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, 230031, China.
  • Wang BL; Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, 230031, China.
  • Shen LJ; Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, 230031, China.
  • Qi S; Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, 230031, China.
  • Liu J; Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, 230031, China.
  • Liu J; Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, 230031, China.
  • Wang WC; Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, 230031, China.
  • Liu QS; Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, 230031, China.
Acta Pharmacol Sin ; 44(4): 801-810, 2023 Apr.
Article en En | MEDLINE | ID: mdl-36216899
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas Quinasas / Necroptosis Límite: Animals / Humans Idioma: En Año: 2023 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas Quinasas / Necroptosis Límite: Animals / Humans Idioma: En Año: 2023 Tipo del documento: Article