Recombinant Humanized IgG1 Antibody Protects against oxLDL-Induced Oxidative Stress and Apoptosis in Human Monocyte/Macrophage THP-1 Cells by Upregulation of MSRA via Sirt1-FOXO1 Axis.

Zhang, Qi; Li, Zhonghao; Liu, Xianyan; Zhao, Ming

Zhang, Qi; Li, Zhonghao; Liu, Xianyan; Zhao, Ming.

Zhang Q; The First School of Clinical Medicine, Southern Medical University, Guangzhou 510515, China.
Li Z; Department of Pathophysiology, Key Lab for Shock and Microcirculation Research of Guangdong, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.
Liu X; Department of Pathophysiology, Key Lab for Shock and Microcirculation Research of Guangdong, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.
Zhao M; Department of Pathophysiology, Key Lab for Shock and Microcirculation Research of Guangdong, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.

Int J Mol Sci ; 23(19)2022 Oct 03.

Article en En | MEDLINE | ID: mdl-36233020

Asunto(s)

Metionina Sulfóxido Reductasas; Sirtuina 1; Apoptosis; Proteína Forkhead Box O1/metabolismo; Humanos; Inmunoglobulina G/metabolismo; Inmunoglobulina G/farmacología; Lipoproteínas LDL/metabolismo; Lipoproteínas LDL/farmacología; Macrófagos/metabolismo; Metionina Sulfóxido Reductasas/metabolismo; Monocitos/metabolismo; Estrés Oxidativo; Sirtuina 1/genética; Sirtuina 1/metabolismo; Células THP-1; Factores de Transcripción/metabolismo; Regulación hacia Arriba

Palabras clave

MSRA; SIRT1-FOXO1 axis; apoptosis; oxidative stress

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Metionina Sulfóxido Reductasas / Sirtuina 1 Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Año: 2022 Tipo del documento: Article

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