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Nociceptor neurons direct goblet cells via a CGRP-RAMP1 axis to drive mucus production and gut barrier protection.
Yang, Daping; Jacobson, Amanda; Meerschaert, Kimberly A; Sifakis, Joseph Joy; Wu, Meng; Chen, Xi; Yang, Tiandi; Zhou, Youlian; Anekal, Praju Vikas; Rucker, Rachel A; Sharma, Deepika; Sontheimer-Phelps, Alexandra; Wu, Glendon S; Deng, Liwen; Anderson, Michael D; Choi, Samantha; Neel, Dylan; Lee, Nicole; Kasper, Dennis L; Jabri, Bana; Huh, Jun R; Johansson, Malin; Thiagarajah, Jay R; Riesenfeld, Samantha J; Chiu, Isaac M.
  • Yang D; Department of Immunology, Harvard Medical School, Boston, MA 02115, USA.
  • Jacobson A; Department of Immunology, Harvard Medical School, Boston, MA 02115, USA.
  • Meerschaert KA; Department of Immunology, Harvard Medical School, Boston, MA 02115, USA.
  • Sifakis JJ; Department of Chemistry, University of Chicago, Chicago, IL 60637, USA.
  • Wu M; Department of Immunology, Harvard Medical School, Boston, MA 02115, USA.
  • Chen X; Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.
  • Yang T; Department of Immunology, Harvard Medical School, Boston, MA 02115, USA.
  • Zhou Y; Department of Immunology, Harvard Medical School, Boston, MA 02115, USA.
  • Anekal PV; MicRoN Core, Harvard Medical School, Boston, MA 02115, USA.
  • Rucker RA; Department of Immunology, Harvard Medical School, Boston, MA 02115, USA.
  • Sharma D; Department of Medicine, University of Chicago, Chicago, IL 60637, USA.
  • Sontheimer-Phelps A; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USA.
  • Wu GS; Department of Immunology, Harvard Medical School, Boston, MA 02115, USA.
  • Deng L; Department of Immunology, Harvard Medical School, Boston, MA 02115, USA.
  • Anderson MD; Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.
  • Choi S; Department of Immunology, Harvard Medical School, Boston, MA 02115, USA.
  • Neel D; Department of Immunology, Harvard Medical School, Boston, MA 02115, USA.
  • Lee N; Department of Immunology, Harvard Medical School, Boston, MA 02115, USA.
  • Kasper DL; Department of Immunology, Harvard Medical School, Boston, MA 02115, USA.
  • Jabri B; Department of Medicine, University of Chicago, Chicago, IL 60637, USA; Committee on Immunology, University of Chicago, Chicago, IL 60637, USA; Department of Pathology and Pediatrics, University of Chicago, Chicago, IL 60637, USA.
  • Huh JR; Department of Immunology, Harvard Medical School, Boston, MA 02115, USA.
  • Johansson M; Department of Medical Biochemistry, Institute of Biomedicine, University of Gothenburg, Gothenburg 40530, Sweden.
  • Thiagarajah JR; Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.
  • Riesenfeld SJ; Department of Medicine, University of Chicago, Chicago, IL 60637, USA; Committee on Immunology, University of Chicago, Chicago, IL 60637, USA; Pritzker School of Molecular Engineering, University of Chicago, Chicago, IL 60637, USA; Institute for Biophysical Dynamics, University of Chicago, Chicago,
  • Chiu IM; Department of Immunology, Harvard Medical School, Boston, MA 02115, USA. Electronic address: isaac_chiu@hms.harvard.edu.
Cell ; 185(22): 4190-4205.e25, 2022 10 27.
Article en En | MEDLINE | ID: mdl-36243004
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Colitis / Células Caliciformes Límite: Animals / Humans Idioma: En Año: 2022 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Colitis / Células Caliciformes Límite: Animals / Humans Idioma: En Año: 2022 Tipo del documento: Article