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First Occurrence of Megastigmane Glucosides in a Plant of Retama Genus.
Ouissem Bensaid, Sara; Carbone, Marianna; Palomba, Letizia; Bicha, Sabrina; Bentamene, Ali; Carannante, Arianna; Gavagnin, Margherita; Letizia Ciavatta, Maria.
  • Ouissem Bensaid S; Consiglio Nazionale delle Ricerche (CNR), Istituto di Chimica Biomolecolare (ICB), Via Campi Flegrei, 34, 80078, Pozzuoli (Na), Italy.
  • Carbone M; University of Mentouri Brothers Constantine 1, Unit of Valorization of Natural Resources, Bioactive Molecules and Physicochemical and Biological Analyzes (VARENBIOMOL), Department of Chemistry, Faculty of Exact Sciences, Constantine, 25000, Algeria.
  • Palomba L; Consiglio Nazionale delle Ricerche (CNR), Istituto di Chimica Biomolecolare (ICB), Via Campi Flegrei, 34, 80078, Pozzuoli (Na), Italy.
  • Bicha S; Consiglio Nazionale delle Ricerche (CNR), Istituto di Chimica Biomolecolare (ICB), Via Campi Flegrei, 34, 80078, Pozzuoli (Na), Italy.
  • Bentamene A; University of Urbino 'Carlo Bo', Department of Biomolecular Sciences, Via Santa Chiara, 27, 61029, Urbino, Italy.
  • Carannante A; University of Mentouri Brothers Constantine 1, Unit of Valorization of Natural Resources, Bioactive Molecules and Physicochemical and Biological Analyzes (VARENBIOMOL), Department of Chemistry, Faculty of Exact Sciences, Constantine, 25000, Algeria.
  • Gavagnin M; University of Mentouri Brothers Constantine 1, Unit of Valorization of Natural Resources, Bioactive Molecules and Physicochemical and Biological Analyzes (VARENBIOMOL), Department of Chemistry, Faculty of Exact Sciences, Constantine, 25000, Algeria.
  • Letizia Ciavatta M; Consiglio Nazionale delle Ricerche (CNR), Istituto di Chimica Biomolecolare (ICB), Via Campi Flegrei, 34, 80078, Pozzuoli (Na), Italy.
Chem Biodivers ; 19(11): e202200675, 2022 Nov.
Article en En | MEDLINE | ID: mdl-36253121
ABSTRACT
Chemical investigation of Retama sphaerocarpa collected in Algeria resulted in the isolation of two megastigmane glucosides, compounds 1 and 2, along with a series of isoflavones and phenol derivatives. Compound 1, named retamoside, was new and its structure was determined by extensive application of spectroscopic methods, including HRMS, 1D and 2D NMR and CD. The anti-inflammatory properties of co-occurring main megastigmane, saurobaccioside B (2) and structurally related vomifoliol (3) on LPS-stimulated murine macrophages RAW 274.7 have been evaluated.
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Norisoprenoides / Fabaceae Límite: Animals País como asunto: Africa Idioma: En Año: 2022 Tipo del documento: Article
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Norisoprenoides / Fabaceae Límite: Animals País como asunto: Africa Idioma: En Año: 2022 Tipo del documento: Article