First Occurrence of Megastigmane Glucosides in a Plant of Retama Genus.
Chem Biodivers
; 19(11): e202200675, 2022 Nov.
Article
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| MEDLINE
| ID: mdl-36253121
ABSTRACT
Chemical investigation of Retama sphaerocarpa collected in Algeria resulted in the isolation of two megastigmane glucosides, compounds 1 and 2, along with a series of isoflavones and phenol derivatives. Compound 1, named retamoside, was new and its structure was determined by extensive application of spectroscopic methods, including HRMS, 1D and 2D NMR and CD. The anti-inflammatory properties of co-occurring main megastigmane, saurobaccioside B (2) and structurally related vomifoliol (3) on LPS-stimulated murine macrophages RAW 274.7 have been evaluated.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Norisoprenoides
/
Fabaceae
Límite:
Animals
País como asunto:
Africa
Idioma:
En
Año:
2022
Tipo del documento:
Article