Distribution of trimipramine and its major metabolites in a fatal overdose case.
J Anal Toxicol
; 11(4): 168-70, 1987.
Article
en En
| MEDLINE
| ID: mdl-3626529
ABSTRACT
A fatality following ingestion of the tricyclic antidepressant trimipramine (Surmontil) is described. Quantitation was performed by high-performance liquid chromatography. Trimipramine and desmethyltrimipramine concentrations were 4.8 and 2.1 mg/L, respectively, in postmortem blood. The concentration of trimipramine, desmethyltrimipramine, and their respective 2-hydroxy metabolites were also measured in liver and urine. Analysis of gastric contents revealed a tricyclic antidepressant drug. These findings are compared to previously published reports of trimipramine-related fatalities.
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Banco de datos:
MEDLINE
Asunto principal:
Trimipramina
/
Dibenzazepinas
Límite:
Adult
/
Humans
/
Male
Idioma:
En
Año:
1987
Tipo del documento:
Article