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Human dihydrofolate reductase inhibition effect of 1-Phenylpyrazolo[3,4-d]pyrimidines: Synthesis, antitumor evaluation and molecular modeling study.
Salem, Ibrahim M; Mostafa, Samia M; Salama, Ismail; El-Sabbagh, Osama I; A H Hegazy, Wael; Ibrahim, Tarek S.
  • Salem IM; Medicinal Chemistry Department, Faculty of Pharmacy, Suez Canal University, Ismailia 41522, Egypt. Electronic address: Dr_Ibrahim_m@yahoo.com.
  • Mostafa SM; Medicinal Chemistry Department, Faculty of Pharmacy, Suez Canal University, Ismailia 41522, Egypt.
  • Salama I; Medicinal Chemistry Department, Faculty of Pharmacy, Suez Canal University, Ismailia 41522, Egypt.
  • El-Sabbagh OI; Medicinal Chemistry Department, Faculty of Pharmacy, Zagazig University, Zagazig 44519, Egypt.
  • A H Hegazy W; Department of Microbiology and Immunology, Faculty of Pharmacy, Zagazig University, Zagazig 44519, Egypt; Pharmacy Program, Department of Pharmaceutical Sciences, Oman College of Health Sciences, Muscat 113, Oman.
  • Ibrahim TS; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Zagazig University, Zagazig 44519, Egypt. Electronic address: tmabrahem@kau.edu.sa.
Bioorg Chem ; 129: 106207, 2022 Dec.
Article en En | MEDLINE | ID: mdl-36270170
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Pirazoles / Pirimidinas / Tetrahidrofolato Deshidrogenasa / Antagonistas del Ácido Fólico / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Female / Humans Idioma: En Año: 2022 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Pirazoles / Pirimidinas / Tetrahidrofolato Deshidrogenasa / Antagonistas del Ácido Fólico / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Female / Humans Idioma: En Año: 2022 Tipo del documento: Article