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Broad transcriptomic dysregulation occurs across the cerebral cortex in ASD.
Gandal, Michael J; Haney, Jillian R; Wamsley, Brie; Yap, Chloe X; Parhami, Sepideh; Emani, Prashant S; Chang, Nathan; Chen, George T; Hoftman, Gil D; de Alba, Diego; Ramaswami, Gokul; Hartl, Christopher L; Bhattacharya, Arjun; Luo, Chongyuan; Jin, Ting; Wang, Daifeng; Kawaguchi, Riki; Quintero, Diana; Ou, Jing; Wu, Ye Emily; Parikshak, Neelroop N; Swarup, Vivek; Belgard, T Grant; Gerstein, Mark; Pasaniuc, Bogdan; Geschwind, Daniel H.
  • Gandal MJ; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, CA, USA. michael.gandal@pennmedicine.upenn.edu.
  • Haney JR; Center for Autism Research and Treatment, Semel Institute of Neuroscience and Human Behavior, University of California, Los Angeles, CA, USA. michael.gandal@pennmedicine.upenn.edu.
  • Wamsley B; Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, University of California, Los Angeles, CA, USA. michael.gandal@pennmedicine.upenn.edu.
  • Yap CX; Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, CA, USA. michael.gandal@pennmedicine.upenn.edu.
  • Parhami S; Lifespan Brain Institute at Penn Medicine and The Children's Hospital of Philadelphia, Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA. michael.gandal@pennmedicine.upenn.edu.
  • Emani PS; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.
  • Chang N; Center for Autism Research and Treatment, Semel Institute of Neuroscience and Human Behavior, University of California, Los Angeles, CA, USA.
  • Chen GT; Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.
  • Hoftman GD; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.
  • de Alba D; Center for Autism Research and Treatment, Semel Institute of Neuroscience and Human Behavior, University of California, Los Angeles, CA, USA.
  • Ramaswami G; Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.
  • Hartl CL; Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.
  • Bhattacharya A; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.
  • Luo C; Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.
  • Jin T; Mater Research Institute, University of Queensland, Brisbane, Queensland, Australia.
  • Wang D; Institute for Molecular Biosciences, University of Queensland, Brisbane, Queensland, Australia.
  • Kawaguchi R; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.
  • Quintero D; Center for Autism Research and Treatment, Semel Institute of Neuroscience and Human Behavior, University of California, Los Angeles, CA, USA.
  • Ou J; Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.
  • Wu YE; Computational Biology & Bioinformatics Program, Yale University, New Haven, CT, USA.
  • Parikshak NN; Computational Biology & Bioinformatics Program, Yale University, New Haven, CT, USA.
  • Swarup V; Center for Autism Research and Treatment, Semel Institute of Neuroscience and Human Behavior, University of California, Los Angeles, CA, USA.
  • Belgard TG; Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.
  • Gerstein M; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.
  • Pasaniuc B; Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.
  • Geschwind DH; Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.
Nature ; 611(7936): 532-539, 2022 Nov.
Article en En | MEDLINE | ID: mdl-36323788
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Variación Genética / Corteza Cerebral / Transcriptoma / Trastorno del Espectro Autista Límite: Humans Idioma: En Año: 2022 Tipo del documento: Article
Texto completo
Imprimir
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PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Variación Genética / Corteza Cerebral / Transcriptoma / Trastorno del Espectro Autista Límite: Humans Idioma: En Año: 2022 Tipo del documento: Article