Melt Crystallization of Celecoxib-Carbamazepine Cocrystals with the Synchronized Release of Drugs.

Chen, An; Cai, Peishan; Luo, Minqian; Guo, Minshan; Cai, Ting

Chen, An; Cai, Peishan; Luo, Minqian; Guo, Minshan; Cai, Ting.

Chen A; Department of Pharmaceutics, School of Pharmacy, China Pharmaceutical University, Nanjing, 210009, China.
Cai P; Department of Pharmaceutics, School of Pharmacy, China Pharmaceutical University, Nanjing, 210009, China.
Luo M; Department of Pharmaceutics, School of Pharmacy, China Pharmaceutical University, Nanjing, 210009, China.
Guo M; Department of Pharmaceutics, School of Pharmacy, China Pharmaceutical University, Nanjing, 210009, China.
Cai T; Department of Pharmaceutics, School of Pharmacy, China Pharmaceutical University, Nanjing, 210009, China. tcai@cpu.edu.cn.

Pharm Res ; 40(2): 567-577, 2023 Feb.

Article en En | MEDLINE | ID: mdl-36348133

Asunto(s)

Carbamazepina; Cristalización; Celecoxib; Solubilidad; Estabilidad de Medicamentos; Carbamazepina/química; Difracción de Rayos X; Rastreo Diferencial de Calorimetría

Palabras clave

celecoxib-carbamazepine cocrystals; hot-melt extrusion; melt crystallization; synchronized release

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