Apigenin attenuates inflammatory response in allergic rhinitis mice by inhibiting the TLR4/MyD88/NF-&#954;B signaling pathway.

Li, Huajing; Zhang, Hongmei; Zhao, Hua

Apigenin attenuates inflammatory response in allergic rhinitis mice by inhibiting the TLR4/MyD88/NF-κB signaling pathway.

Li, Huajing; Zhang, Hongmei; Zhao, Hua.

Li H; Department of Otolaryngology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Zhang H; Department of Otolaryngology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Zhao H; Department of Pharmacy, Affiliated Hospital of Medical College of Xi'an Jiaotong University, Shaanxi Provincial Cancer Hospital, Xi'an, China.

Environ Toxicol ; 38(2): 253-265, 2023 Feb.

Article en En | MEDLINE | ID: mdl-36350155

Asunto(s)

Apigenina; Factor 88 de Diferenciación Mieloide; FN-kappa B; Rinitis Alérgica; Receptor Toll-Like 4; Animales; Ratones; Apigenina/farmacología; Apigenina/uso terapéutico; beta-N-Acetilhexosaminidasas/metabolismo; Citocinas/metabolismo; Modelos Animales de Enfermedad; Histamina/toxicidad; Inmunoglobulina E; Inmunoglobulina G/toxicidad; Inmunoglobulina G/metabolismo; Interleucina-4; Leucocitos Mononucleares/metabolismo; Lipopolisacáridos/farmacología; Ratones Endogámicos BALB C; Factor 88 de Diferenciación Mieloide/metabolismo; FN-kappa B/metabolismo; Ovalbúmina/farmacología; Rinitis Alérgica/inducido químicamente; Rinitis Alérgica/tratamiento farmacológico; Transducción de Señal; Células Th2; Receptor Toll-Like 4/metabolismo

Palabras clave

HMC-1 mast cells; TLR4/MyD88/NF-κB pathway; allergic rhinitis; apigenin; inflammatory response

Texto completo

Imprimir

XML

PubMed Links

Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: FN-kappa B / Apigenina / Receptor Toll-Like 4 / Factor 88 de Diferenciación Mieloide / Rinitis Alérgica Límite: Animals Idioma: En Año: 2023 Tipo del documento: Article

Texto completo

Imprimir

XML

PubMed Links

Search on Google