Analyses of Transcriptomics Cell Signalling for Pre-Screening Applications in the Integrated Approach for Testing and Assessment of Non-Genotoxic Carcinogens.

Oku, Yusuke; Madia, Federica; Lau, Pierre; Paparella, Martin; McGovern, Timothy; Luijten, Mirjam; Jacobs, Miriam N

Oku, Yusuke; Madia, Federica; Lau, Pierre; Paparella, Martin; McGovern, Timothy; Luijten, Mirjam; Jacobs, Miriam N.

Oku Y; The Organisation for Economic Cooperation and Development (OECD), 2 Rue Andre Pascal, 75016 Paris, France.
Madia F; European Commission, Joint Research Centre (JRC), Via Enrico Fermi, 2749, 21027 Ispra, Italy.
Lau P; Istituto Italiano di Tecnologia, 16163 Genova, Italy.
Paparella M; Institute of Medical Biochemistry, Biocenter, Medical University of Innsbruck, Innrain 80, 6020 Innbruck, Austria.
McGovern T; US Food and Drug Administration (FDA), 10903 New Hampshire Avenue, Silver Spring, MD 20901, USA.
Luijten M; Centre for Health Protection, National Institute for Public Health and the Environment (RIVM), Antonie van Leeuwenhoeklaan 9, Bilthoven, 3721 MA Utrecht, The Netherlands.
Jacobs MN; Centre for Radiation, Chemical and Environmental Hazard (CRCE), Public Health England (PHE), Chilton OX11 0RQ, Oxfordshire, UK.

Int J Mol Sci ; 23(21)2022 Oct 22.

Article en En | MEDLINE | ID: mdl-36361516

Asunto(s)

Carcinógenos; Transcriptoma; Humanos; Carcinógenos/toxicidad; Bioensayo; Carcinogénesis; Pruebas de Carcinogenicidad/métodos

Palabras clave

carcinogenicity; gene expression; integrated approaches to testing and assessment (IATA); non-genotoxic carcinogen(s) (NGTxC(s)); organisation for economic co-operation and development (OECD); transcriptomics

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Carcinógenos / Transcriptoma Tipo de estudio: Diagnostic_studies / Screening_studies Límite: Humans Idioma: En Año: 2022 Tipo del documento: Article

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