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A high-throughput MALDI-TOF MS biochemical screen for small molecule inhibitors of the antigen aminopeptidase ERAP1.
Müller, Leonie; Burton, Amy K; Tayler, Chloe L; Rowedder, James E; Hutchinson, Jonathan P; Peace, Simon; Quayle, Julie M; Leveridge, Melanie V; Annan, Roland S; Trost, Matthias; Peltier-Heap, Rachel E; Dueñas, Maria Emilia.
  • Müller L; Newcastle University, Faculty of Medical Sciences, Biosciences Institute, Framlington Place, Newcastle Upon Tyne NE2 4HH, United Kingdom.
  • Burton AK; GSK, Discovery Analytical, Gunnels Wood Rd, Stevenage SG1 2NY, United Kingdom.
  • Tayler CL; GSK, Discovery Analytical, Gunnels Wood Rd, Stevenage SG1 2NY, United Kingdom.
  • Rowedder JE; GSK, Screening, Profiling and Mechanistic Biology, Gunnels Wood Rd, Stevenage SG1 2NY, United Kingdom.
  • Hutchinson JP; GSK, Screening, Profiling and Mechanistic Biology, Gunnels Wood Rd, Stevenage SG1 2NY, United Kingdom.
  • Peace S; GSK, Medicinal Chemistry, Gunnels Wood Rd, Stevenage SG1 2NY, United Kingdom.
  • Quayle JM; GSK, Discovery Analytical, Gunnels Wood Rd, Stevenage SG1 2NY, United Kingdom.
  • Leveridge MV; GSK, Screening, Profiling and Mechanistic Biology, Gunnels Wood Rd, Stevenage SG1 2NY, United Kingdom.
  • Annan RS; GSK, Discovery Analytical, Gunnels Wood Rd, Stevenage SG1 2NY, United Kingdom.
  • Trost M; Newcastle University, Faculty of Medical Sciences, Biosciences Institute, Framlington Place, Newcastle Upon Tyne NE2 4HH, United Kingdom. Electronic address: matthias.trost@ncl.ac.uk.
  • Peltier-Heap RE; GSK, Discovery Analytical, Gunnels Wood Rd, Stevenage SG1 2NY, United Kingdom. Electronic address: rachel.x.heap@gsk.com.
  • Dueñas ME; Newcastle University, Faculty of Medical Sciences, Biosciences Institute, Framlington Place, Newcastle Upon Tyne NE2 4HH, United Kingdom. Electronic address: maria.duenas@ncl.ac.uk.
SLAS Discov ; 28(1): 3-11, 2023 01.
Article en En | MEDLINE | ID: mdl-36414185
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Ensayos Analíticos de Alto Rendimiento / Aminopeptidasas Idioma: En Año: 2023 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Ensayos Analíticos de Alto Rendimiento / Aminopeptidasas Idioma: En Año: 2023 Tipo del documento: Article