Melatonin suppresses serum starvation-induced autophagy of ovarian granulosa cells in premature ovarian insufficiency.

Wu, Di; Zhao, Wenjie; Xu, Chengjuan; Zhou, Xin; Leng, Xia; Li, Yanmin

Wu, Di; Zhao, Wenjie; Xu, Chengjuan; Zhou, Xin; Leng, Xia; Li, Yanmin.

Wu D; Department of Reproductive Medicine, Weifang People's Hospital, No.151 Guangwen Street, Kuiwen DistrictShandong Province, Weifang City, 261041, China.
Zhao W; Department of Reproductive Medicine, Weifang People's Hospital, No.151 Guangwen Street, Kuiwen DistrictShandong Province, Weifang City, 261041, China.
Xu C; Department of Gynecology, Shouguang People's Hospital, Weifang, 262700, Shandong, China.
Zhou X; Quality Management Office of Weifang People's Hospital, Weifang, 262700, China.
Leng X; Department of Reproductive Medicine, Weifang People's Hospital, No.151 Guangwen Street, Kuiwen DistrictShandong Province, Weifang City, 261041, China.
Li Y; Department of Reproductive Medicine, Weifang People's Hospital, No.151 Guangwen Street, Kuiwen DistrictShandong Province, Weifang City, 261041, China. drliyanmin@163.com.

BMC Womens Health ; 22(1): 474, 2022 11 24.

Article en En | MEDLINE | ID: mdl-36434569

Asunto(s)

Melatonina; Menopausia Prematura; MicroARNs; Insuficiencia Ovárica Primaria; Humanos; Femenino; Proteínas Proto-Oncogénicas c-akt/metabolismo; Melatonina/farmacología; Fosfatidilinositol 3-Quinasas/metabolismo; MicroARNs/genética; Serina-Treonina Quinasas TOR/metabolismo; Células de la Granulosa/metabolismo; Autofagia

Palabras clave

Autophagy; Granulosa cells; Melatonin; PI3K-Akt-mTOR pathway; Premature ovarian insufficiency; Serum starvation; Stat3; miR-15a-5p

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Menopausia Prematura / Insuficiencia Ovárica Primaria / MicroARNs / Melatonina Límite: Female / Humans Idioma: En Año: 2022 Tipo del documento: Article

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