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In silico identification of a ß2-adrenoceptor allosteric site that selectively augments canonical ß2AR-Gs signaling and function.
Shah, Sushrut D; Lind, Christoffer; De Pascali, Francesco; Penn, Raymond B; MacKerell, Alexander D; Deshpande, Deepak A.
  • Shah SD; Center for Translational Medicine, Jane and Leonard Korman Respiratory Institute, Philadelphia, PA 19107.
  • Lind C; Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland Computer-Aided Drug Design Center, University of Maryland, Baltimore, MD 21201.
  • De Pascali F; Department of Biochemistry and Molecular Biology, Thomas Jefferson University, Philadelphia, PA 19107.
  • Penn RB; Center for Translational Medicine, Jane and Leonard Korman Respiratory Institute, Philadelphia, PA 19107.
  • MacKerell AD; Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland Computer-Aided Drug Design Center, University of Maryland, Baltimore, MD 21201.
  • Deshpande DA; Center for Translational Medicine, Jane and Leonard Korman Respiratory Institute, Philadelphia, PA 19107.
Proc Natl Acad Sci U S A ; 119(49): e2214024119, 2022 12 06.
Article en En | MEDLINE | ID: mdl-36449547
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Asma / Receptores Adrenérgicos beta 2 Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Humans Idioma: En Año: 2022 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Asma / Receptores Adrenérgicos beta 2 Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Humans Idioma: En Año: 2022 Tipo del documento: Article