The splicing regulators TIA1 and TIAL1 are required for the expression of the DNA damage repair machinery during B cell lymphopoiesis.

Osma-Garcia, Ines C; Capitan-Sobrino, Dunja; Mouysset, Mailys; Aubert, Yann; Maloudi, Orlane; Turner, Martin; Diaz-Muñoz, Manuel D

Osma-Garcia, Ines C; Capitan-Sobrino, Dunja; Mouysset, Mailys; Aubert, Yann; Maloudi, Orlane; Turner, Martin; Diaz-Muñoz, Manuel D.

Osma-Garcia IC; Toulouse Institute for Infectious and Inflammatory Diseases (INFINITy), Inserm UMR1291, CNRS UMR5051, University Paul Sabatier, CHU Purpan, Toulouse 31024, France.
Capitan-Sobrino D; Toulouse Institute for Infectious and Inflammatory Diseases (INFINITy), Inserm UMR1291, CNRS UMR5051, University Paul Sabatier, CHU Purpan, Toulouse 31024, France.
Mouysset M; Toulouse Institute for Infectious and Inflammatory Diseases (INFINITy), Inserm UMR1291, CNRS UMR5051, University Paul Sabatier, CHU Purpan, Toulouse 31024, France.
Aubert Y; Toulouse Institute for Infectious and Inflammatory Diseases (INFINITy), Inserm UMR1291, CNRS UMR5051, University Paul Sabatier, CHU Purpan, Toulouse 31024, France.
Maloudi O; Toulouse Institute for Infectious and Inflammatory Diseases (INFINITy), Inserm UMR1291, CNRS UMR5051, University Paul Sabatier, CHU Purpan, Toulouse 31024, France.
Turner M; Immunology Program, The Babraham Institute, Babraham Research Campus, Cambridge CB22 3AT, UK.
Diaz-Muñoz MD; Toulouse Institute for Infectious and Inflammatory Diseases (INFINITy), Inserm UMR1291, CNRS UMR5051, University Paul Sabatier, CHU Purpan, Toulouse 31024, France. Electronic address: manuel.diaz-munoz@inserm.fr.

Cell Rep ; 41(12): 111869, 2022 12 20.

Article en En | MEDLINE | ID: mdl-36543128

Asunto(s)

Linfopoyesis; Proteínas de Unión a Poli(A); Antígeno Intracelular 1 de las Células T/genética; Antígeno Intracelular 1 de las Células T/metabolismo; Proteínas de Unión a Poli(A)/metabolismo; Linfopoyesis/genética; Empalme del ARN; Sitios de Empalme de ARN; Reparación del ADN; Daño del ADN

Palabras clave

B cell development; CP: Developmental biology; CP: Molecular biology; DNA damage repair; RNA splicing; TIA1; TIAL1; apoptosis; immunoglobulin VDJ recombination; post-transcriptional gene regulation; pro-B cells; progenitor B cells

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas de Unión a Poli(A) / Linfopoyesis Idioma: En Año: 2022 Tipo del documento: Article

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas de Unión a Poli(A) / Linfopoyesis Idioma: En Año: 2022 Tipo del documento: Article