[Microecological regulative principles of human gastrointestinal flora]. / Mikroökologische Regulationsprinzipien der menschlichen Gastrointestinalflora.

ABSTRACT

In the course of coevolution of man and microorganisms the macroorganism must have developed mechanisms which allow a qualitative and quantitative regulation in his microbial colonization. On the several places, microbial growth is limited by various factors. Adherence ability of microorganisms belongs to the special colonization events. An uninhibited colonization begins if regulative factors are omitted. Factors of the host are only partially able to kill the microorganisms. Microbes possess signal receptors managing adaptation to environmental changes. If a strategy of growth and multiplication is not realizable such factors change to a strategy of survival. Very likely, these common microbiological principles are valid to the gastrointestinal tract, too.