Prevalence of an insufficient vitamin D status at the onset of a spinal cord injury - a cross-sectional study.
Spinal Cord
; 61(3): 211-217, 2023 03.
Article
en En
| MEDLINE
| ID: mdl-36581746
ABSTRACT
STUDY DESIGN:
A cross-sectional study.OBJECTIVE:
This study aimed to investigate the vitamin D status after acute spinal cord injury (SCI) onset.SETTING:
Specialized SCI rehabilitation center in Switzerland.METHODS:
Patients admitted to the center after an acute SCI onset were included. The prevalence of a deficient (25(OH)D ≤ 50 nmol/l), insufficient (50 < 25(OH)D ≤ 75 nmol/l) and sufficient (25(OH)D > 75 nmol/l) vitamin D status were determined after admission. Vitamin D status was compared between different patient groups based on demographic and SCI characteristics. The occurrence of bed rest, falls and pressure injuries were also assessed.RESULTS:
In total, 87 patients (median (interquartile range); 53 (39-67) years, 25 females, 66 traumatic SCI, 54 paraplegia) were included. Assessed a median of 15 (9-22) days after SCI onset, median vitamin D status was 41 (26-57) (range 8-155) nmol/l. The majority of patients had a deficient (67%, 95% confidence interval (95% CI) 0.56-0.76) or insufficient (25%, 95% CI 0.17-0.36) vitamin D status. A moderate negative correlation was found between vitamin D status and body mass index (p = 0.003). A moderate positive correlation was found between vitamin D and calcium status (p = 0.01).CONCLUSION:
A deficient or insufficient vitamin D status directly after SCI onset is highly prevalent. Vitamin D status should be carefully observed during acute SCI rehabilitation. We recommend that all patients with recent SCI onset should receive vitamin D supplementation with a dosage depending on their actual vitamin D status.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Traumatismos de la Médula Espinal
/
Deficiencia de Vitamina D
Tipo de estudio:
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Límite:
Female
/
Humans
Idioma:
En
Año:
2023
Tipo del documento:
Article