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An international survey of current management practices for polymyalgia rheumatica by general practitioners and rheumatologists.
Donskov, Agnete Overgaard; Mackie, Sarah Louise; Hauge, Ellen Margrethe; Toro-Gutiérrez, Carlos Enrique; Hansen, Ib Tønder; Hemmig, Andrea Katharina; Van der Maas, Aatke; Gheita, Tamer; Nielsen, Berit Dalsgaard; Douglas, Karen M J; Conway, Richard; Rezus, Elena; Dasgupta, Bhaskar; Monti, Sara; Matteson, Eric L; Sattui, Sebastian E; Matza, Mark; Ocampo, Vanessa; Gromova, Margarita; Grainger, Rebecca; Bran, Andrea; Appenzeller, Simone; Goecke, Annelise; Colman, Nelly; Keen, Helen I; Kuwana, Masataka; Gupta, Latika; Salim, Babur; Harifi, Ghita; Erraoui, Mariam; Ziade, Nelly; Al-Ani, Nizar Abdulateef; Ajibade, Adeola; Knitza, Johannes; Frølund, Line; Yates, Max; Pimentel-Quiroz, Victor R; Lyrio, Andre Marun; Sandovici, Maria; Van der Geest, Kornelis S M; Helliwell, Toby; Brouwer, Elisabeth; Dejaco, Christian; Keller, Kresten Krarup.
  • Donskov AO; Department of Rheumatology, Aarhus University Hospital, Aarhus, Denmark.
  • Mackie SL; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK.
  • Hauge EM; NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
  • Toro-Gutiérrez CE; Department of Rheumatology, Aarhus University Hospital, Aarhus, Denmark.
  • Hansen IT; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
  • Hemmig AK; Reference center for Osteoporosis, Rheumatology & Dermatology, Cali, Colombia.
  • Van der Maas A; Department of Rheumatology, Aarhus University Hospital, Aarhus, Denmark.
  • Gheita T; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
  • Nielsen BD; Department of Rheumatology, University Hospital Basel, Basel, Switzerland.
  • Douglas KMJ; Rheumatology Department, St Maartenskliniek, Nijmegen, Netherlands.
  • Conway R; Rheumatology and Clinical Immunology, Cairo University, Cairo, Egypt.
  • Rezus E; Department of Medicine, The Regional Hospital in Horsens, Horsens, Denmark.
  • Dasgupta B; Department of Rheumatology, Dudley Group NHS FT, Dudley, UK.
  • Monti S; Department of Rheumatology, St. James's Hospital, Dublin, Ireland.
  • Matteson EL; Department of Rheumatology, 'Grigore T. Popa' University of Medicine and Pharmacy, Iasi, Romania.
  • Sattui SE; Department of Rheumatology, Southend University Hospital, Southend, UK.
  • Matza M; Division of Rheumatology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
  • Ocampo V; Department of Internal Medicine and Therapeutics, Università di Pavia, Pavia, Italy.
  • Gromova M; Division of Rheumatology, Mayo Clinic College of Medicine and Science, Rochester, USA.
  • Grainger R; Division of Rheumatology and Clinical Immunology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
  • Bran A; Rheumatology Unit, Massachusetts General Hospital, Boston, USA.
  • Appenzeller S; Rheumatology Department-Scarborough Health Network and Kensington Eye Institute, University of Toronto-Center for Prognosis Studies in Rheumatic Diseases, Toronto Western Hospital, Toronto, Canada.
  • Goecke A; Faculty Therapy, Pirogov National Russian Research Medical University, Moscow, Russian Federation.
  • Colman N; Department of Medicine, University of Otago Wellington, Wellington, New Zealand.
  • Keen HI; Department of Medicine, Universidad Francisco Marroquín, Guatemala City, Guatemala.
  • Kuwana M; Department of Orthopedics, Rheumatology and Traumatology-School of Medical Science, University of Campinas, Campinas, Brazil.
  • Gupta L; Rheumatology Section, Department of Medicine, University of Chile's Clinical Hospital, Santiago, Chile.
  • Salim B; Universidad Nacional de Asunción, Hospital de Clinicas, Asunción, Paraguay.
  • Harifi G; Medical School, UWA, Perth Australia, Rheumatology Department, Fiona Stanley Hospital, Perth, Australia.
  • Erraoui M; Department of Allergy and Rheumatology, Nippon Medical School, Tokyo, Japan.
  • Ziade N; Department of Rheumatology, Royal Wolverhampton Hospital NHS Trust, Wolverhampton, UK.
  • Al-Ani NA; Department of Rheumatology, City Hospital, Sandwell and West Birmingham Hospitals NHS Trust, Birmingham, UK.
  • Ajibade A; Division of Musculoskeletal and Dermatological Sciences, Centre for Musculoskeletal Research, School of Biological Sciences, The University of Manchester, Manchester, UK.
  • Knitza J; Rheumatology, Fauji Foundation Hospital Rawalpindi, Rawalpindi, Pakistan.
  • Frølund L; Rheumatology, Mediclinic Parkview Hospital, Dubai Health Authority, Dubai, United Arab Emirates.
  • Yates M; Faculty of Medicine and Pharmacy, Department of Rheumatology, Ibn Zohr University, Agadir, Morocco.
  • Pimentel-Quiroz VR; Rheumatology, Saint-Joseph University, Beirut, Lebanon.
  • Lyrio AM; Rheumatology Unit, Department of Medicine, University of Baghdad, Bagdhad, Iraq.
  • Sandovici M; Department of Rheumatology, Royal Wolverhampton Hospital NHS Trust, Wolverhampton, UK.
  • Van der Geest KSM; Rheumatology Unit, Internal Medicine Department, Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Nigeria.
  • Helliwell T; German Centrum for Immune Therapy, Friedrich-Alexander-University Erlangen Nürnberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany.
  • Brouwer E; Department of Rheumatology, Aarhus University Hospital, Aarhus, Denmark.
  • Dejaco C; Centre for Epidemiology, Norwich Medical School, University of East Anglia, Norwich, UK.
  • Keller KK; Department of Rheumatology, Norfolk and Norwich University Hospital, Norwich, UK.
Rheumatology (Oxford) ; 62(8): 2797-2805, 2023 08 01.
Article en En | MEDLINE | ID: mdl-36637182
ABSTRACT

OBJECTIVES:

To explore current management practices for PMR by general practitioners (GPs) and rheumatologists including implications for clinical trial recruitment.

METHODS:

An English language questionnaire was constructed by a working group of rheumatologists and GPs from six countries. The questionnaire focused on 1 Respondent characteristics; 2 Referral practices; 3 Treatment with glucocorticoids; 4 Diagnostics; 5 Comorbidities; and 6 Barriers to research. The questionnaire was distributed to rheumatologists and GPs worldwide via members of the International PMR/Giant Cell Arteritis Study Group.

RESULTS:

In total, 394 GPs and 937 rheumatologists responded to the survey. GPs referred a median of 25% of their suspected PMR patients for diagnosis and 50% of these were returned to their GP for management. In general, 39% of rheumatologists evaluated patients with suspected PMR >2 weeks after referral, and a median of 50% of patients had started prednisolone before rheumatologist evaluation. Direct comparison of initial treatment showed that the percentage prescribing >25 mg prednisolone daily for patients was 30% for GPs and 12% for rheumatologists. Diagnostic imaging was rarely used. More than half (56%) of rheumatologists experienced difficulties recruiting people with PMR to clinical trials.

CONCLUSION:

This large international survey indicates that a large proportion of people with PMR are not referred for diagnosis, and that the proportion of treatment-naive patients declined with increasing time from referral to assessment. Strategies are needed to change referral and management of people with PMR, to improve clinical practice and facilitate recruitment to clinical trials.
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Polimialgia Reumática / Arteritis de Células Gigantes / Médicos Generales Tipo de estudio: Clinical_trials / Diagnostic_studies Límite: Humans Idioma: En Año: 2023 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Polimialgia Reumática / Arteritis de Células Gigantes / Médicos Generales Tipo de estudio: Clinical_trials / Diagnostic_studies Límite: Humans Idioma: En Año: 2023 Tipo del documento: Article