Identification of Human UDP-Glucuronosyltransferase Involved in Gypensapogenin C Glucuronidation and Species Differences.

Chen, Juan; Qin, Lin; Wu, Xingdong; Tan, Daopeng; Lu, Yanliu; Du, Yimei; Wu, Di; He, Yuqi

Chen, Juan; Qin, Lin; Wu, Xingdong; Tan, Daopeng; Lu, Yanliu; Du, Yimei; Wu, Di; He, Yuqi.

Chen J; Guizhou Engineering Research Center of Industrial Key-Technology for Dendrobium Nobile, Zunyi Medical University, Zunyi 563000, China.
Qin L; Guizhou Engineering Research Center of Industrial Key-Technology for Dendrobium Nobile, Zunyi Medical University, Zunyi 563000, China.
Wu X; Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi 563000, China.
Tan D; Guizhou Engineering Research Center of Industrial Key-Technology for Dendrobium Nobile, Zunyi Medical University, Zunyi 563000, China.
Lu Y; Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi 563000, China.
Du Y; Guizhou Engineering Research Center of Industrial Key-Technology for Dendrobium Nobile, Zunyi Medical University, Zunyi 563000, China.
Wu D; Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi 563000, China.
He Y; Guizhou Engineering Research Center of Industrial Key-Technology for Dendrobium Nobile, Zunyi Medical University, Zunyi 563000, China.

Int J Mol Sci ; 24(2)2023 Jan 11.

Article en En | MEDLINE | ID: mdl-36674970

Asunto(s)

Glucurónidos; Espectrometría de Masas en Tándem; Humanos; Ratas; Animales; Cromatografía Liquida; Cinética; Especificidad de la Especie; Glucurónidos/metabolismo; Isoenzimas/metabolismo; Microsomas Hepáticos/metabolismo; Glucuronosiltransferasa/metabolismo; UDP Glucuronosiltransferasa 1A9; Uridina Difosfato/metabolismo

Palabras clave

UGT1A4; glucuronidation; gypensapogenin C; human liver microsomes; species differences

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Glucurónidos / Espectrometría de Masas en Tándem Tipo de estudio: Diagnostic_studies Límite: Animals / Humans Idioma: En Año: 2023 Tipo del documento: Article

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