LINC01004-SPI1 axis-activated SIGLEC9 in tumor-associated macrophages induces radioresistance and the formation of immunosuppressive tumor microenvironment in esophageal squamous cell carcinoma.

Zhao, Fen; Tian, Hui; Wang, Yungang; Zhang, Jianbo; Liu, Fang; Fu, Lei

Zhao, Fen; Tian, Hui; Wang, Yungang; Zhang, Jianbo; Liu, Fang; Fu, Lei.

Zhao F; Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, 250117, Shandong, People's Republic of China.
Tian H; Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong University, Jinan, 250117, Shandong, People's Republic of China.
Wang Y; Department of Radiation Oncology, Qilu Hospital of Shandong University, Jinan, 250012, Shandong, People's Republic of China.
Zhang J; Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, 250117, Shandong, People's Republic of China.
Liu F; Departments of Pathology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, 250117, Shandong, People's Republic of China.
Fu L; Department of Imaging, Shandong Medical College, Jinan, 250002, Shandong, People's Republic of China.

Cancer Immunol Immunother ; 72(6): 1835-1851, 2023 Jun.

Article en En | MEDLINE | ID: mdl-36688997

Asunto(s)

Neoplasias Esofágicas; Carcinoma de Células Escamosas de Esófago; Animales; Humanos; Antígenos CD; Línea Celular Tumoral; Neoplasias Esofágicas/patología; Carcinoma de Células Escamosas de Esófago/radioterapia; Carcinoma de Células Escamosas de Esófago/patología; Lectinas Similares a la Inmunoglobulina de Unión a Ácido Siálico; Microambiente Tumoral; Macrófagos Asociados a Tumores/metabolismo; ARN Largo no Codificante/genética; ARN Largo no Codificante/metabolismo

Palabras clave

Esophageal squamous cell carcinoma; MUC1; Radioresistance; SIGLEC9; Tumor-associated macrophages

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Esofágicas / Carcinoma de Células Escamosas de Esófago Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Animals / Humans Idioma: En Año: 2023 Tipo del documento: Article

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