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Small-Molecule Polθ Inhibitors Provide Safe and Effective Tumor Radiosensitization in Preclinical Models.
Rodriguez-Berriguete, Gonzalo; Ranzani, Marco; Prevo, Remko; Puliyadi, Rathi; Machado, Nicole; Bolland, Hannah R; Millar, Val; Ebner, Daniel; Boursier, Marie; Cerutti, Aurora; Cicconi, Alessandro; Galbiati, Alessandro; Grande, Diego; Grinkevich, Vera; Majithiya, Jayesh B; Piscitello, Desiree; Rajendra, Eeson; Stockley, Martin L; Boulton, Simon J; Hammond, Ester M; Heald, Robert A; Smith, Graeme C M; Robinson, Helen M R; Higgins, Geoff S.
  • Rodriguez-Berriguete G; Department of Oncology, University of Oxford, Oxford, United Kingdom.
  • Ranzani M; Artios Pharma, Babraham Research Campus, Cambridge, United Kingdom.
  • Prevo R; Department of Oncology, University of Oxford, Oxford, United Kingdom.
  • Puliyadi R; Department of Oncology, University of Oxford, Oxford, United Kingdom.
  • Machado N; Department of Oncology, University of Oxford, Oxford, United Kingdom.
  • Bolland HR; Department of Oncology, University of Oxford, Oxford, United Kingdom.
  • Millar V; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
  • Ebner D; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
  • Boursier M; Artios Pharma, Babraham Research Campus, Cambridge, United Kingdom.
  • Cerutti A; Artios Pharma, Babraham Research Campus, Cambridge, United Kingdom.
  • Cicconi A; Artios Pharma, Babraham Research Campus, Cambridge, United Kingdom.
  • Galbiati A; Artios Pharma, Babraham Research Campus, Cambridge, United Kingdom.
  • Grande D; Artios Pharma, Babraham Research Campus, Cambridge, United Kingdom.
  • Grinkevich V; Artios Pharma, Babraham Research Campus, Cambridge, United Kingdom.
  • Majithiya JB; Artios Pharma, Babraham Research Campus, Cambridge, United Kingdom.
  • Piscitello D; Artios Pharma, Babraham Research Campus, Cambridge, United Kingdom.
  • Rajendra E; Artios Pharma, Babraham Research Campus, Cambridge, United Kingdom.
  • Stockley ML; Artios Pharma, Babraham Research Campus, Cambridge, United Kingdom.
  • Boulton SJ; Artios Pharma, Babraham Research Campus, Cambridge, United Kingdom.
  • Hammond EM; The Francis Crick Institute, London, United Kingdom.
  • Heald RA; Department of Oncology, University of Oxford, Oxford, United Kingdom.
  • Smith GCM; Artios Pharma, Babraham Research Campus, Cambridge, United Kingdom.
  • Robinson HMR; Artios Pharma, Babraham Research Campus, Cambridge, United Kingdom.
  • Higgins GS; Artios Pharma, Babraham Research Campus, Cambridge, United Kingdom.
Clin Cancer Res ; 29(8): 1631-1642, 2023 04 14.
Article en En | MEDLINE | ID: mdl-36689546
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Límite: Humans Idioma: En Año: 2023 Tipo del documento: Article
Texto completo
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XML
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Límite: Humans Idioma: En Año: 2023 Tipo del documento: Article