Dissociative Transition State in Hepatitis Delta Virus Ribozyme Catalysis.

Weissman, Benjamin; Ekesan, Sölen; Lin, Hsuan-Chun; Gardezi, Shahbaz; Li, Nan-Sheng; Giese, Timothy J; McCarthy, Erika; Harris, Michael E; York, Darrin M; Piccirilli, Joseph A

Weissman, Benjamin; Ekesan, Sölen; Lin, Hsuan-Chun; Gardezi, Shahbaz; Li, Nan-Sheng; Giese, Timothy J; McCarthy, Erika; Harris, Michael E; York, Darrin M; Piccirilli, Joseph A.

Weissman B; Department of Chemistry and Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago, Illinois 60637, United States.
Ekesan S; Laboratory for Biomolecular Simulation Research, Institute for Quantitative Biomedicine, Department of Chemistry and Chemical Biology, Rutgers University, Piscataway, New Jersey 08854, United States.
Lin HC; Department of Chemistry, University of Florida, Gainesville, Florida 32611, United States.
Gardezi S; Department of Chemistry, University of Florida, Gainesville, Florida 32611, United States.
Li NS; Department of Chemistry and Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago, Illinois 60637, United States.
Giese TJ; Laboratory for Biomolecular Simulation Research, Institute for Quantitative Biomedicine, Department of Chemistry and Chemical Biology, Rutgers University, Piscataway, New Jersey 08854, United States.
McCarthy E; Laboratory for Biomolecular Simulation Research, Institute for Quantitative Biomedicine, Department of Chemistry and Chemical Biology, Rutgers University, Piscataway, New Jersey 08854, United States.
Harris ME; Department of Chemistry, University of Florida, Gainesville, Florida 32611, United States.
York DM; Laboratory for Biomolecular Simulation Research, Institute for Quantitative Biomedicine, Department of Chemistry and Chemical Biology, Rutgers University, Piscataway, New Jersey 08854, United States.
Piccirilli JA; Department of Chemistry and Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago, Illinois 60637, United States.

J Am Chem Soc ; 145(5): 2830-2839, 2023 02 08.

Article en En | MEDLINE | ID: mdl-36706353

Asunto(s)

ARN Catalítico; ARN Catalítico/química; Virus de la Hepatitis Delta/genética; Virus de la Hepatitis Delta/metabolismo; ARN/química; Catálisis; Dominio Catalítico; Conformación de Ácido Nucleico; Cinética

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