Regional redistribution of CB1 cannabinoid receptors in human foetal brains with Down's syndrome and their functional modifications in Ts65Dn<sup>+/+</sup> mice.

Patthy, Ágoston; Hanics, János; Zachar, Gergely; Kovács, Gábor G; Harkany, Tibor; Alpár, Alán

Regional redistribution of CB1 cannabinoid receptors in human foetal brains with Down's syndrome and their functional modifications in Ts65Dn^+/+ mice.

Patthy, Ágoston; Hanics, János; Zachar, Gergely; Kovács, Gábor G; Harkany, Tibor; Alpár, Alán.

Patthy Á; Department of Anatomy, Semmelweis University, Budapest, Hungary.
Hanics J; Department of Anatomy, Semmelweis University, Budapest, Hungary.
Zachar G; SE NAP Research Group of Experimental Neuroanatomy and Developmental Biology, Semmelweis University, Budapest, Hungary.
Kovács GG; Department of Anatomy, Semmelweis University, Budapest, Hungary.
Harkany T; Institute of Neurology, Medical University of Vienna, Vienna, Austria.
Alpár A; Department of Laboratory Medicine and Pathobiology and Tanz Centre for Research in Neurodegenerative Disease, University of Toronto, Toronto, Canada.

Neuropathol Appl Neurobiol ; 49(1): e12887, 2023 02.

Article en En | MEDLINE | ID: mdl-36716771

Asunto(s)

Síndrome de Down; Animales; Humanos; Ratones; Encéfalo/metabolismo; Síndrome de Down/metabolismo; Endocannabinoides/metabolismo; Ratones Transgénicos; Receptor Cannabinoide CB1/metabolismo; Receptores de Cannabinoides/metabolismo

Palabras clave

cannabinoid receptor; developmental delay; endocannabinoid system; genetic brain disease; neurodevelopmental disorder; trisomy

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Síndrome de Down Límite: Animals / Humans Idioma: En Año: 2023 Tipo del documento: Article

Texto completo

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PubMed Links

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Síndrome de Down Límite: Animals / Humans Idioma: En Año: 2023 Tipo del documento: Article