The Lipid Raft-Associated Protein Stomatin Is Required for Accumulation of Dectin-1 in the Phagosomal Membrane and for Full Activity of Macrophages against Aspergillus fumigatus.

Goldmann, Marie; Schmidt, Franziska; Cseresnyés, Zoltán; Orasch, Thomas; Jahreis, Susanne; Hartung, Susann; Figge, Marc Thilo; von Lilienfeld-Toal, Marie; Heinekamp, Thorsten; Brakhage, Axel A

Goldmann, Marie; Schmidt, Franziska; Cseresnyés, Zoltán; Orasch, Thomas; Jahreis, Susanne; Hartung, Susann; Figge, Marc Thilo; von Lilienfeld-Toal, Marie; Heinekamp, Thorsten; Brakhage, Axel A.

Goldmann M; Department of Molecular and Applied Microbiology, Leibniz Institute for Natural Product Research and Infection Biology-Hans Knöll Institute (Leibniz-HKI), Jena, Germany.
Schmidt F; Department of Microbiology and Molecular Biology, Institute of Microbiology, Friedrich Schiller University Jena, Jena, Germany.
Cseresnyés Z; Department of Molecular and Applied Microbiology, Leibniz Institute for Natural Product Research and Infection Biology-Hans Knöll Institute (Leibniz-HKI), Jena, Germany.
Orasch T; Department of Microbiology and Molecular Biology, Institute of Microbiology, Friedrich Schiller University Jena, Jena, Germany.
Jahreis S; Research Group Applied Systems Biology, Leibniz-HKI, Jena, Germany.
Hartung S; Department of Molecular and Applied Microbiology, Leibniz Institute for Natural Product Research and Infection Biology-Hans Knöll Institute (Leibniz-HKI), Jena, Germany.
Figge MT; Department of Infections in Hematology/Oncology, Leibniz-HKI, Jena, Germany.
von Lilienfeld-Toal M; Department of Infections in Hematology/Oncology, Leibniz-HKI, Jena, Germany.
Heinekamp T; Research Group Applied Systems Biology, Leibniz-HKI, Jena, Germany.
Brakhage AA; Institute of Microbiology, Faculty of Biological Sciences, Friedrich Schiller University Jena, Jena, Germany.

mSphere ; 8(1): e0052322, 2023 02 21.

Article en En | MEDLINE | ID: mdl-36719247

Asunto(s)

Aspergillus fumigatus; Macrófagos; Humanos; Aspergillus fumigatus/metabolismo; Macrófagos/microbiología; Fagosomas; Proteínas de la Membrana/metabolismo; Microdominios de Membrana/metabolismo

Palabras clave

Aspergillus fumigatus; CRISPR/Cas9; dectin-1; lipid rafts; phagocytosis; phagosomal maturation; phagosomes; stomatin

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Aspergillus fumigatus / Macrófagos Tipo de estudio: Risk_factors_studies Límite: Humans Idioma: En Año: 2023 Tipo del documento: Article

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