Design and off-target prediction for antisense oligomers targeting bacterial mRNAs with the MASON web server.

Jung, Jakob; Popella, Linda; Do, Phuong Thao; Pfau, Patrick; Vogel, Jörg; Barquist, Lars

Jung, Jakob; Popella, Linda; Do, Phuong Thao; Pfau, Patrick; Vogel, Jörg; Barquist, Lars.

Jung J; Institute for Molecular Infection Biology, University of Würzburg, 97080 Würzburg, Germany.
Popella L; Institute for Molecular Infection Biology, University of Würzburg, 97080 Würzburg, Germany.
Do PT; Institute for Molecular Infection Biology, University of Würzburg, 97080 Würzburg, Germany.
Pfau P; Helmholtz Institute for RNA-based Infection Research (HIRI), Helmholtz Centre for Infection Research (HZI), 97080 Würzburg, Germany.
Vogel J; Faculty of Medicine, University of Würzburg, 97080 Würzburg, Germany.
Barquist L; Institute for Molecular Infection Biology, University of Würzburg, 97080 Würzburg, Germany.

RNA ; 29(5): 570-583, 2023 05.

Article en En | MEDLINE | ID: mdl-36750372

Asunto(s)

Ácidos Nucleicos de Péptidos; ARN Mensajero/genética; ARN Mensajero/química; Ácidos Nucleicos de Péptidos/genética; Ácidos Nucleicos de Péptidos/farmacología; Ácidos Nucleicos de Péptidos/química; Oligonucleótidos Antisentido/farmacología; Bacterias/genética; ARN; Salmonella typhimurium/genética

Palabras clave

RNA sequencing; antisense antibiotics; antisense oligomers; off-targets; peptide nucleic acid; web server

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Ácidos Nucleicos de Péptidos Tipo de estudio: Prognostic_studies / Risk_factors_studies Idioma: En Año: 2023 Tipo del documento: Article

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