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European study showed that children with congenital anomalies often underwent multiple surgical procedures at different ages across Europe.
Garne, Ester; Loane, Maria; Tan, Joachim; Ballardini, Elisa; Brigden, Joanna; Cavero-Carbonell, Clara; Coi, Alessio; Damkjaer, Mads; Garcia-Villodre, Laura; Gissler, Mika; Given, Joanne; Heino, Anna; Jordan, Sue; Limb, Elizabeth; Neville, Amanda; Rissmann, Anke; Santoro, Michele; Scanlon, Ieuan; Urhoj, Stine Kjaer; Wellesley, Diana; Morris, Joan.
  • Garne E; Department of Paediatrics and Adolescent Medicine, Lillebaelt Hospital, University Hospital of Southern Denmark, Kolding, Denmark.
  • Loane M; Faculty of Life and Health Sciences, Ulster University, Coleraine, UK.
  • Tan J; Population Health Research Institute, St George's, University of London, London, UK.
  • Ballardini E; Neonatal Intensive Care Unit, Paediatric Section, IMER Registry (Emilia Romagna Registry of Birth Defects), Department of Medical Sciences, University of Ferrara, Ferrara, Italy.
  • Brigden J; Population Health Research Institute, St George's, University of London, London, UK.
  • Cavero-Carbonell C; Rare Diseases Research Unit, Foundation for the Promotion of Health and Biomedical Research in the Valencian Region, Valencia, Spain.
  • Coi A; Unit of Epidemiology of Rare Diseases and Congenital Anomalies, Institute of Clinical Physiology, National Research Council, Pisa, Italy.
  • Damkjaer M; Department of Paediatrics and Adolescent Medicine, Lillebaelt Hospital, University Hospital of Southern Denmark, Kolding, Denmark.
  • Garcia-Villodre L; Department of Regional Health Research, University of Southern Denmark, Odense, Denmark.
  • Gissler M; Rare Diseases Research Unit, Foundation for the Promotion of Health and Biomedical Research in the Valencian Region, Valencia, Spain.
  • Given J; Department of Knowledge Brokers, THL Finnish Institute for Health and Welfare Helsinki, Helsinki, Finland.
  • Heino A; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
  • Jordan S; Faculty of Life and Health Sciences, Ulster University, Coleraine, UK.
  • Limb E; Department of Knowledge Brokers, THL Finnish Institute for Health and Welfare Helsinki, Helsinki, Finland.
  • Neville A; Faculty of Medicine, Health and Life Science, Swansea University, Swansea, UK.
  • Rissmann A; Population Health Research Institute, St George's, University of London, London, UK.
  • Santoro M; Emilia Romagna Registry of Birth Defects and Center for Clinical and Epidemiological Research, University of Ferrara, Azienda Ospedaliero-Universitaria di Ferrara, Ferrara, Italy.
  • Scanlon I; Malformation Monitoring Centre Saxony-Anhalt, Medical Faculty Otto-von-Guericke-University Magdeburg, Magdeburg, Germany.
  • Urhoj SK; Unit of Epidemiology of Rare Diseases and Congenital Anomalies, Institute of Clinical Physiology, National Research Council, Pisa, Italy.
  • Wellesley D; Faculty of Medicine, Health and Life Science, Swansea University, Swansea, UK.
  • Morris J; Department of Paediatrics and Adolescent Medicine, Lillebaelt Hospital, University Hospital of Southern Denmark, Kolding, Denmark.
Acta Paediatr ; 112(6): 1304-1311, 2023 06.
Article en En | MEDLINE | ID: mdl-36823678
ABSTRACT

AIM:

Children with congenital anomalies often require surgery but data on the burden of surgery for these children are limited.

METHODS:

A population-based record-linkage study in Finland, Wales and regions of Denmark, England, Italy and Spain. A total of 91 504 children with congenital anomalies born in 1995-2014 were followed to their tenth birthday or the end of 2015. Electronic linkage to hospital databases provided data on inpatient surgical procedures and meta-analyses of surgical procedures were performed by age groups.

RESULTS:

The percentage of children having surgery in the first year was 38% with some differences across regions and 14% also underwent surgery at age 1-4 years. Regional differences in age at the time of their first surgical procedure were observed for children with cleft palate, hydronephrosis, hypospadias, clubfoot and craniosynostosis. The children had a median of 2.0 (95% CI 1.98, 2.02) surgical procedures before age 5 years with children with oesophageal atresia having the highest median number of procedures (4.5; 95% CI 3.3, 5.8).

CONCLUSION:

A third of children with congenital anomalies required surgery during infancy and often more than one procedure was needed before age 5 years. There was no European consensus on the preferred age for surgery for some anomalies.
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Pie Equinovaro / Hipospadias Límite: Adult / Child / Child, preschool / Female / Humans / Infant / Male / Pregnancy País como asunto: Europa Idioma: En Año: 2023 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Pie Equinovaro / Hipospadias Límite: Adult / Child / Child, preschool / Female / Humans / Infant / Male / Pregnancy País como asunto: Europa Idioma: En Año: 2023 Tipo del documento: Article