Validation of a liquid chromatography-tandem mass spectrometry method for simultaneous quantification of N,N-dimethylacetamide and N-monomethylacetamide in pediatric plasma.

Rosser, Sebastian P A; McLachlan, Andrew J; Hempel, Georg; Chung, Jason; Shaw, Peter J; Keogh, Steven J; Nath, Christa E

Rosser, Sebastian P A; McLachlan, Andrew J; Hempel, Georg; Chung, Jason; Shaw, Peter J; Keogh, Steven J; Nath, Christa E.

Rosser SPA; The Children's Hospital at Westmead Clinical School, University of Sydney, Sydney, Australia.
McLachlan AJ; Department of Biochemistry, The Children's Hospital at Westmead, Sydney, Australia.
Hempel G; Cancer Centre for Children, The Children's Hospital at Westmead, Sydney, Australia.
Chung J; Sydney Pharmacy School, Faculty of Medicine and Health, University of Sydney, Sydney, Australia.
Shaw PJ; Institute for Pharmaceutical and Medicinal Chemistry and Clinical Pharmacy, University of Münster, Sydney, Germany.
Keogh SJ; The Children's Hospital at Westmead Clinical School, University of Sydney, Sydney, Australia.
Nath CE; Department of Biochemistry, The Children's Hospital at Westmead, Sydney, Australia.

J Sep Sci ; 46(10): e2201003, 2023 May.

Article en En | MEDLINE | ID: mdl-36879545

Asunto(s)

Busulfano; Espectrometría de Masas en Tándem; Niño; Humanos; Espectrometría de Masas en Tándem/métodos; Metanol; Cromatografía Liquida/métodos; Cromatografía Líquida de Alta Presión/métodos

Palabras clave

N,N-dimethylacetamide; N-monomethylacetamide; liquid chromatography-tandem mass spectrometry; method validation; pharmacokinetics

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Busulfano / Espectrometría de Masas en Tándem Límite: Child / Humans Idioma: En Año: 2023 Tipo del documento: Article

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