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Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains.
Wang, Jing Yang John; Khmelinskaia, Alena; Sheffler, William; Miranda, Marcos C; Antanasijevic, Aleksandar; Borst, Andrew J; Torres, Susana V; Shu, Chelsea; Hsia, Yang; Nattermann, Una; Ellis, Daniel; Walkey, Carl; Ahlrichs, Maggie; Chan, Sidney; Kang, Alex; Nguyen, Hannah; Sydeman, Claire; Sankaran, Banumathi; Wu, Mengyu; Bera, Asim K; Carter, Lauren; Fiala, Brooke; Murphy, Michael; Baker, David; Ward, Andrew B; King, Neil P.
  • Wang JYJ; Department of Biochemistry, University of Washington, Seattle, WA 98195.
  • Khmelinskaia A; Institute for Protein Design, University of Washington, Seattle, WA 98195.
  • Sheffler W; Graduate Program in Molecular and Cellular Biology, University of Washington, Seattle, WA 98195.
  • Miranda MC; Department of Biochemistry, University of Washington, Seattle, WA 98195.
  • Antanasijevic A; Institute for Protein Design, University of Washington, Seattle, WA 98195.
  • Borst AJ; Transdisciplinary Research Area "Building Blocks of Matter and Fundamental Interactions", University of Bonn, 53113 Bonn, Germany.
  • Torres SV; Life and Medical Sciences Institute, University of Bonn, 53121 Bonn, Germany.
  • Shu C; Department of Biochemistry, University of Washington, Seattle, WA 98195.
  • Hsia Y; Institute for Protein Design, University of Washington, Seattle, WA 98195.
  • Nattermann U; Department of Biochemistry, University of Washington, Seattle, WA 98195.
  • Ellis D; Institute for Protein Design, University of Washington, Seattle, WA 98195.
  • Walkey C; Department of Integrative, Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037.
  • Ahlrichs M; Scripps Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037.
  • Chan S; Department of Biochemistry, University of Washington, Seattle, WA 98195.
  • Kang A; Institute for Protein Design, University of Washington, Seattle, WA 98195.
  • Nguyen H; Department of Biochemistry, University of Washington, Seattle, WA 98195.
  • Sydeman C; Institute for Protein Design, University of Washington, Seattle, WA 98195.
  • Sankaran B; Department of Biochemistry, University of Washington, Seattle, WA 98195.
  • Wu M; Institute for Protein Design, University of Washington, Seattle, WA 98195.
  • Bera AK; Department of Biochemistry, University of Washington, Seattle, WA 98195.
  • Carter L; Institute for Protein Design, University of Washington, Seattle, WA 98195.
  • Fiala B; Department of Biochemistry, University of Washington, Seattle, WA 98195.
  • Murphy M; Institute for Protein Design, University of Washington, Seattle, WA 98195.
  • Baker D; Graduate Program in Biological Physics, Structure and Design, University of Washington, Seattle, WA 98195.
  • Ward AB; Department of Biochemistry, University of Washington, Seattle, WA 98195.
  • King NP; Institute for Protein Design, University of Washington, Seattle, WA 98195.
Proc Natl Acad Sci U S A ; 120(11): e2214556120, 2023 03 14.
Article en En | MEDLINE | ID: mdl-36888664

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Vacunas / Nanopartículas Tipo de estudio: Guideline Idioma: En Año: 2023 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Vacunas / Nanopartículas Tipo de estudio: Guideline Idioma: En Año: 2023 Tipo del documento: Article