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HBV with precore and basal core promoter mutations exhibits a high replication phenotype and causes ER stress-mediated cell death in humanized liver chimeric mice.
Uchida, Takuro; Imamura, Michio; Hayes, C Nelson; Suehiro, Yosuke; Teraoka, Yuji; Ohya, Kazuki; Aikata, Hiroshi; Abe-Chayama, Hiromi; Ishida, Yuji; Tateno, Chise; Hara, Yuichi; Hino, Keisuke; Okamoto, Toru; Matsuura, Yoshiharu; Aizaki, Hideki; Wake, Kenjiro; Kohara, Michinori; Liang, T Jake; Oka, Shiro; Chayama, Kazuaki.
  • Uchida T; Department of Gastroenterology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
  • Imamura M; Department of Gastroenterology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
  • Hayes CN; Department of Gastroenterology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
  • Suehiro Y; Department of Gastroenterology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
  • Teraoka Y; Department of Gastroenterology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
  • Ohya K; Department of Gastroenterology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
  • Aikata H; Department of Gastroenterology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
  • Abe-Chayama H; Research Center for Hepatology and Gastroenterology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
  • Ishida Y; Center for Medical Specialist Graduate Education and Research, Hiroshima, Japan.
  • Tateno C; Research Center for Hepatology and Gastroenterology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
  • Hara Y; PhoenixBio Co., Ltd., Higashihiroshima, Japan.
  • Hino K; Research Center for Hepatology and Gastroenterology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
  • Okamoto T; PhoenixBio Co., Ltd., Higashihiroshima, Japan.
  • Matsuura Y; Department of Hepatology and Pancreatology, Kawasaki Medical School, Kurashiki, Japan.
  • Aizaki H; Department of Hepatology and Pancreatology, Kawasaki Medical School, Kurashiki, Japan.
  • Wake K; Institute for Advanced Co-creation Studies, Research Institute for Microbial Diseases Osaka University, Osaka, Japan.
  • Kohara M; Center for Infectious Disease Education and Research, Osaka University, Osaka, Japan.
  • Liang TJ; Center for Infectious Disease Education and Research, Osaka University, Osaka, Japan.
  • Oka S; Department of Virus Control, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan.
  • Chayama K; Department of Virology II, National Institute of Infectious Diseases, Tokyo, Japan.
Hepatology ; 78(3): 929-942, 2023 09 01.
Article en En | MEDLINE | ID: mdl-36896966

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Virus de la Hepatitis B / Necrosis Hepática Masiva Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2023 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Virus de la Hepatitis B / Necrosis Hepática Masiva Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2023 Tipo del documento: Article