Antiproliferative Activity, Multikinase Inhibition, Apoptosis- Inducing Effects and Molecular Docking of Novel Isatin-Purine Hybrids.

Alanazi, Ashwag S; Mirgany, Tebyan O; Alsfouk, Aisha A; Alsaif, Nawaf A; Alanazi, Mohammed M

Alanazi, Ashwag S; Mirgany, Tebyan O; Alsfouk, Aisha A; Alsaif, Nawaf A; Alanazi, Mohammed M.

Alanazi AS; Department of Pharmaceutical Sciences, College of Pharmacy, Princess Nourah bint Abdulrahman University, Riyadh 84428, Saudi Arabia.
Mirgany TO; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Alsfouk AA; Department of Pharmaceutical Sciences, College of Pharmacy, Princess Nourah bint Abdulrahman University, Riyadh 84428, Saudi Arabia.
Alsaif NA; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Alanazi MM; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.

Medicina (Kaunas) ; 59(3)2023 Mar 19.

Article en En | MEDLINE | ID: mdl-36984611

Asunto(s)

Antineoplásicos; Isatina; Neoplasias; Humanos; Isatina/farmacología; Isatina/química; Isatina/uso terapéutico; Simulación del Acoplamiento Molecular; Factor A de Crecimiento Endotelial Vascular; Antineoplásicos/farmacología; Antineoplásicos/uso terapéutico; Antineoplásicos/química; Neoplasias/tratamiento farmacológico; Proliferación Celular; Apoptosis; Purinas/farmacología; Purinas/uso terapéutico; Línea Celular Tumoral

Palabras clave

anticancer; hybrid design; isatin; kinase inhibitor; purine

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Isatina / Neoplasias / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Año: 2023 Tipo del documento: Article

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