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Mapping the dynamic genetic regulatory architecture of HLA genes at single-cell resolution.
Kang, Joyce B; Shen, Amber Z; Sakaue, Saori; Luo, Yang; Gurajala, Saisriram; Nathan, Aparna; Rumker, Laurie; Aguiar, Vitor R C; Valencia, Cristian; Lagattuta, Kaitlyn; Zhang, Fan; Jonsson, Anna Helena; Yazar, Seyhan; Alquicira-Hernandez, Jose; Khalili, Hamed; Ananthakrishnan, Ashwin N; Jagadeesh, Karthik; Dey, Kushal; Daly, Mark J; Xavier, Ramnik J; Donlin, Laura T; Anolik, Jennifer H; Powell, Joseph E; Rao, Deepak A; Brenner, Michael B; Gutierrez-Arcelus, Maria; Raychaudhuri, Soumya.
  • Kang JB; Center for Data Sciences, Brigham and Women's Hospital, Boston, MA, USA.
  • Shen AZ; Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
  • Sakaue S; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.
  • Luo Y; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Gurajala S; Division of Rheumatology, Inflammation, and Immunity, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
  • Nathan A; Center for Data Sciences, Brigham and Women's Hospital, Boston, MA, USA.
  • Rumker L; Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
  • Aguiar VRC; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.
  • Valencia C; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Lagattuta K; Division of Rheumatology, Inflammation, and Immunity, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
  • Zhang F; Center for Data Sciences, Brigham and Women's Hospital, Boston, MA, USA.
  • Jonsson AH; Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
  • Yazar S; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.
  • Alquicira-Hernandez J; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Khalili H; Division of Rheumatology, Inflammation, and Immunity, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
  • Ananthakrishnan AN; Center for Data Sciences, Brigham and Women's Hospital, Boston, MA, USA.
  • Jagadeesh K; Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
  • Dey K; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.
  • Daly MJ; Division of Rheumatology, Inflammation, and Immunity, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
  • Xavier RJ; Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK.
  • Donlin LT; Center for Data Sciences, Brigham and Women's Hospital, Boston, MA, USA.
  • Anolik JH; Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
  • Powell JE; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.
  • Rao DA; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Brenner MB; Division of Rheumatology, Inflammation, and Immunity, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
  • Gutierrez-Arcelus M; Center for Data Sciences, Brigham and Women's Hospital, Boston, MA, USA.
  • Raychaudhuri S; Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
medRxiv ; 2023 Mar 20.
Article en En | MEDLINE | ID: mdl-36993194