Thyroid hormones as biomarkers of lung cancer: a retrospective study.
Ann Med
; 55(1): 2196088, 2023 12.
Article
en En
| MEDLINE
| ID: mdl-37014291
Serum TSH, TT4, TT3, and FT3 levels were significantly decreased in patients with lung cancer.low TT3 concentration was positively associated with age (p < 0.05), sex (p < 0.05), tumor size (p < 0.05) and lymph node metastasis (p < 0.05). Moreover, the concentration of FT3 was dependent on age (p < 0.05) and tumor size (p < 0.05). The serum FT4 concentration was discernible with obviously higher concentration in stage IV patients compared with stage IIII patients (p < 0.05).When FT3 was used in combination with CEA and CYF, the sensitivity and specificity in the screening for stage IIV lung cancer were markedly increased to 85.9% and 97.5%, respectively. When we included FT3, FT4, and CEA in the diagnosis, the AUC was 0.774. The sensitivity and specificity of screening for stage 0 lung cancer were increased to 70.2% and 75.2%, respectively.
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Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Triyodotironina
/
Neoplasias Pulmonares
Tipo de estudio:
Diagnostic_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Límite:
Female
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Humans
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Pregnancy
Idioma:
En
Año:
2023
Tipo del documento:
Article