Benzo[b]naphtho[2,1-d]furans and 2-Phenylnaphthalenes from Streblus usambarensis.
J Nat Prod
; 86(4): 1010-1018, 2023 04 28.
Article
en En
| MEDLINE
| ID: mdl-37043719
ABSTRACT
Three new benzo[b]naphtho[2,1-d]furans, usambarins A-C (1-3), five new 2-phenylnaphthalenes, usambarins D-H (4-8), a new flavan (9), and a new phenyl-1-benzoxepin (10) as well as two known compounds (11 and 12) were isolated from the extract of the stem and roots of Streblus usambarensis (Moraceae). The structures were deduced using NMR spectroscopic and mass spectrometric analyses, and those of compounds 1 and 4 were confirmed by X-ray crystallography. Usambarin D (4) demonstrated moderate antibacterial activity (MIC 9.0 µM) against Bacillus subtilis, while none of the tested compounds were effective against Escherichia coli.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Moraceae
/
Furanos
Idioma:
En
Año:
2023
Tipo del documento:
Article