Lack of preference for diazepam in anxious volunteers.
Arch Gen Psychiatry
; 43(6): 533-41, 1986 Jun.
Article
en En
| MEDLINE
| ID: mdl-3707286
ABSTRACT
Using a choice procedure, these experiments tested whether diazepam is more highly preferred by anxious subjects than by normal control subjects. Subjects first sampled and then chose between two capsules containing diazepam (5 or 10 mg) and placebo, or amphetamine (5 mg) and placebo. The number of times each drug was chosen over placebo and the subjective effects of the drugs were measured. Anxious subjects did not differ from controls in their drug choices. Most subjects chose diazepam less often than placebo, especially at the higher dose, whereas they chose amphetamine more often than placebo. The subjective drug effects (including anxiety reduction after diazepam) were similar for anxious and nonanxious subjects, despite predrug differences in anxiety. The results suggest that individuals with high anxiety are not at greater risk for dependence on antianxiety drugs.
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Banco de datos:
MEDLINE
Asunto principal:
Trastornos de Ansiedad
/
Conducta de Elección
/
Diazepam
Tipo de estudio:
Clinical_trials
/
Etiology_studies
/
Risk_factors_studies
Límite:
Adult
/
Female
/
Humans
/
Male
Idioma:
En
Año:
1986
Tipo del documento:
Article