Cucurbitacin IIb attenuates cancer cachexia induced skeletal muscle atrophy by regulating the IL-6/STAT3/FoxO signaling pathway.

Wang, Yaxian; Sun, Xipeng; Yang, Quanjun; Guo, Cheng

Wang, Yaxian; Sun, Xipeng; Yang, Quanjun; Guo, Cheng.

Wang Y; Department of Pharmacy, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Sun X; School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Yang Q; Department of Pharmacy, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Guo C; Department of Pharmacy, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Phytother Res ; 37(8): 3380-3393, 2023 Aug.

Article en En | MEDLINE | ID: mdl-37073890

Asunto(s)

Caquexia; Neoplasias; Humanos; Caquexia/tratamiento farmacológico; Caquexia/etiología; Caquexia/metabolismo; Interleucina-6/metabolismo; Calidad de Vida; Neoplasias/patología; Atrofia Muscular/tratamiento farmacológico; Atrofia Muscular/etiología; Transducción de Señal; Músculo Esquelético/metabolismo; Fibras Musculares Esqueléticas/metabolismo; Factor de Transcripción STAT3/metabolismo

Palabras clave

IL-6/STAT3/FoxO pathway; STAT3; cancer cachexia; cucurbitacin IIb; skeleta muscle atrophy

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Caquexia / Neoplasias Tipo de estudio: Etiology_studies Límite: Humans Idioma: En Año: 2023 Tipo del documento: Article

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