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Carbon nanosheets to unravel the production of bioactive compounds from microalgae: A robust approach in drug discovery.
Agarwal, Aakanksha; Selvam, Abhyavartin; Majood, Misba; Agrawal, Omnarayan; Chakrabarti, Sandip; Mukherjee, Monalisa.
  • Agarwal A; Amity Institute of Click Chemistry Research and Studies, Amity University Uttar Pradesh, Noida 201313, India.
  • Selvam A; Amity Institute of Click Chemistry Research and Studies, Amity University Uttar Pradesh, Noida 201313, India; Amity Institute of Nanotechnology, Amity University Uttar Pradesh, Noida 201313, India.
  • Majood M; Amity Institute of Click Chemistry Research and Studies, Amity University Uttar Pradesh, Noida 201313, India.
  • Agrawal O; Amity Institute of Click Chemistry Research and Studies, Amity University Uttar Pradesh, Noida 201313, India.
  • Chakrabarti S; Amity Institute of Nanotechnology, Amity University Uttar Pradesh, Noida 201313, India.
  • Mukherjee M; Amity Institute of Click Chemistry Research and Studies, Amity University Uttar Pradesh, Noida 201313, India. Electronic address: mmukherjee@amity.edu.
Drug Discov Today ; 28(6): 103586, 2023 06.
Article en En | MEDLINE | ID: mdl-37080385
ABSTRACT
The conglomeration of active pharmaceutical ingredients (APIs) has influenced the development of life-saving drugs. These APIs are customarily synthetic products, albeit with adverse side effects. Thus, to overcome the bottlenecks associated with synthetically derived APIs, the approach of photocatalytically obtaining bioactive compounds from natural ingredients has emerged. Amid the pool of photoactive nanomaterials, this short review emphasizes the intelligent strategy of exploiting photoactive carbon nanosheets to photocatalytically derive bioactive compounds from natural algal biomass to treat many acute or chronic medical conditions. Carbon nanosheets result in phototrophic harvesting of bioactive compounds from microalgae as a result of their being an effective biocatalyst that increases the rate of photosynthesis. To understand the clinical translation of bioactive compounds, the pharmacodynamics of algal bioactive compounds are highlighted to determine the practicality and feasibility of using this green approach for pharmaceutical drug discovery.
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Microalgas Idioma: En Año: 2023 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Microalgas Idioma: En Año: 2023 Tipo del documento: Article