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Proteomic discovery of chemical probes that perturb protein complexes in human cells.
Lazear, Michael R; Remsberg, Jarrett R; Jaeger, Martin G; Rothamel, Katherine; Her, Hsuan-Lin; DeMeester, Kristen E; Njomen, Evert; Hogg, Simon J; Rahman, Jahan; Whitby, Landon R; Won, Sang Joon; Schafroth, Michael A; Ogasawara, Daisuke; Yokoyama, Minoru; Lindsey, Garrett L; Li, Haoxin; Germain, Jason; Barbas, Sabrina; Vaughan, Joan; Hanigan, Thomas W; Vartabedian, Vincent F; Reinhardt, Christopher J; Dix, Melissa M; Koo, Seong Joo; Heo, Inha; Teijaro, John R; Simon, Gabriel M; Ghosh, Brahma; Abdel-Wahab, Omar; Ahn, Kay; Saghatelian, Alan; Melillo, Bruno; Schreiber, Stuart L; Yeo, Gene W; Cravatt, Benjamin F.
  • Lazear MR; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA.
  • Remsberg JR; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA. Electronic address: remsberg@scripps.edu.
  • Jaeger MG; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA.
  • Rothamel K; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA.
  • Her HL; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA.
  • DeMeester KE; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA.
  • Njomen E; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA.
  • Hogg SJ; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA.
  • Rahman J; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA.
  • Whitby LR; Vividion Therapeutics, 5820 Nancy Ridge Drive, San Diego, CA 92121, USA.
  • Won SJ; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA.
  • Schafroth MA; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA.
  • Ogasawara D; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA.
  • Yokoyama M; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA.
  • Lindsey GL; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA.
  • Li H; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA.
  • Germain J; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA.
  • Barbas S; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA.
  • Vaughan J; Clayton Foundation Laboratories for Peptide Biology, The Salk Institute for Biological Studies, La Jolla, CA, USA.
  • Hanigan TW; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA.
  • Vartabedian VF; Department of Immunology and Microbiology, Scripps Research, La Jolla, CA 92037, USA.
  • Reinhardt CJ; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA.
  • Dix MM; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA.
  • Koo SJ; Molecular and Cellular Pharmacology, Discovery Technologies and Molecular Pharmacology, Janssen Research and Development, Turnhoutseweg 30, 2340 Beerse, Belgium.
  • Heo I; Molecular and Cellular Pharmacology, Discovery Technologies and Molecular Pharmacology, Janssen Research and Development, Turnhoutseweg 30, 2340 Beerse, Belgium.
  • Teijaro JR; Department of Immunology and Microbiology, Scripps Research, La Jolla, CA 92037, USA.
  • Simon GM; Vividion Therapeutics, 5820 Nancy Ridge Drive, San Diego, CA 92121, USA.
  • Ghosh B; Discovery Chemistry, Janssen Research & Development, Spring House, PA 19477, USA.
  • Abdel-Wahab O; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA.
  • Ahn K; Molecular and Cellular Pharmacology, Discovery Technologies and Molecular Pharmacology, Janssen Research and Development, Spring House, PA 19477, USA.
  • Saghatelian A; Clayton Foundation Laboratories for Peptide Biology, The Salk Institute for Biological Studies, La Jolla, CA, USA.
  • Melillo B; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA; Chemical Biology and Therapeutics Science Program, Broad Institute, Cambridge, MA 02142, USA.
  • Schreiber SL; Chemical Biology and Therapeutics Science Program, Broad Institute, Cambridge, MA 02142, USA; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA.
  • Yeo GW; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA.
  • Cravatt BF; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA. Electronic address: cravatt@scripps.edu.
Mol Cell ; 83(10): 1725-1742.e12, 2023 05 18.
Article en En | MEDLINE | ID: mdl-37084731
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Factores de Transcripción / Proteómica Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Año: 2023 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Factores de Transcripción / Proteómica Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Año: 2023 Tipo del documento: Article