Design, synthesis and biological activity evaluation of novel covalent S-acylation inhibitors.

Yu, Wei; Yang, Kan; Zhao, Mengmiao; Liu, Han; You, Zhihao; Liu, Zhenming; Qiao, Xiaoqiang; Song, Yali.

Yu W; Key Laboratory of Pharmaceutical Quality Control of Hebei Province, College of Pharmaceutical Sciences, Hebei University, Baoding, 071002, Hebei, China.
Yang K; Key Laboratory of Pharmaceutical Quality Control of Hebei Province, College of Pharmaceutical Sciences, Hebei University, Baoding, 071002, Hebei, China.
Zhao M; Key Laboratory of Pharmaceutical Quality Control of Hebei Province, College of Pharmaceutical Sciences, Hebei University, Baoding, 071002, Hebei, China.
Liu H; Key Laboratory of Pharmaceutical Quality Control of Hebei Province, College of Pharmaceutical Sciences, Hebei University, Baoding, 071002, Hebei, China.
You Z; Key Laboratory of Pharmaceutical Quality Control of Hebei Province, College of Pharmaceutical Sciences, Hebei University, Baoding, 071002, Hebei, China.
Liu Z; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China.
Qiao X; Key Laboratory of Pharmaceutical Quality Control of Hebei Province, College of Pharmaceutical Sciences, Hebei University, Baoding, 071002, Hebei, China. xiaoqiao@hbu.edu.cn.
Song Y; Key Laboratory of Medicinal Chemistry and Molecular Diagnosis, Ministry of Education, Hebei University, Baoding, 071002, Hebei, China. xiaoqiao@hbu.edu.cn.

Mol Divers ; 2023 Apr 24.

Article en En | MEDLINE | ID: mdl-37093341