MicroRNA-143 acts as a tumor suppressor through Musashi-2/DLL1/Notch1 and Musashi-2/Snail1/MMPs axes in acute myeloid leukemia.

Li, Fanfan; Han, Yixiang; Chen, Rongrong; Jiang, Yinyan; Chen, Cheng; Wang, Xiaofang; Zhou, Jifan; Xu, Qingqing; Jiang, Songfu; Zhang, Si; Yu, Kang; Zhang, Shenghui

Li, Fanfan; Han, Yixiang; Chen, Rongrong; Jiang, Yinyan; Chen, Cheng; Wang, Xiaofang; Zhou, Jifan; Xu, Qingqing; Jiang, Songfu; Zhang, Si; Yu, Kang; Zhang, Shenghui.

Li F; Department of Hematology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325015, Zhejiang, China.
Han Y; Institute of Hematology, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Chen R; Wenzhou Key Laboratory of Hematology, Wenzhou, 325015, Zhejiang, China.
Jiang Y; Institute of Hematology, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Chen C; Wenzhou Key Laboratory of Hematology, Wenzhou, 325015, Zhejiang, China.
Wang X; Central Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Zhou J; Department of Hematology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325015, Zhejiang, China.
Xu Q; Institute of Hematology, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Jiang S; Wenzhou Key Laboratory of Hematology, Wenzhou, 325015, Zhejiang, China.
Zhang S; Department of Hematology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325015, Zhejiang, China.
Yu K; Institute of Hematology, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Zhang S; Wenzhou Key Laboratory of Hematology, Wenzhou, 325015, Zhejiang, China.

J Transl Med ; 21(1): 309, 2023 05 06.

Article en En | MEDLINE | ID: mdl-37149661

Asunto(s)

Leucemia Mieloide Aguda; MicroARNs; Humanos; Animales; Ratones; Leucemia Mieloide Aguda/patología; Genes Supresores de Tumor; Proliferación Celular/genética; Regulación hacia Arriba; Modelos Animales de Enfermedad; MicroARNs/genética; MicroARNs/metabolismo; Línea Celular Tumoral; Receptor Notch1/genética; Receptor Notch1/metabolismo; Proteínas de Unión al ARN/genética

Palabras clave

Acute myeloid leukemia; DLL1; Musashi-2; Snail1; microRNA-143

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Leucemia Mieloide Aguda / MicroARNs Límite: Animals / Humans Idioma: En Año: 2023 Tipo del documento: Article

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Leucemia Mieloide Aguda / MicroARNs Límite: Animals / Humans Idioma: En Año: 2023 Tipo del documento: Article