Identification and validation of novel Blastocystis subtype ST41 in a Colombian patient undergoing colorectal cancer screening.
J Eukaryot Microbiol
; 70(5): e12978, 2023.
Article
en En
| MEDLINE
| ID: mdl-37195413
ABSTRACT
Blastocystis sp. is among the most frequent intestinal protists identified in humans globally. However, characterization of Blastocystis subtype diversity in humans is ongoing. We report here the identification of novel Blastocystis subtype ST41 in a Colombian patient undergoing colorectal cancer screening involving colonoscopy and fecal testing (microscopy, culture, PCR). The full-length ssu rRNA gene sequence of the protist was generated using MinION long-read sequencing technology. The validity of the novel subtype was confirmed via phylogenetic and pairwise distance analyses of the full-length ST41 sequence and all other valid subtypes. The study provides reference material essential for conducting subsequent experimental studies.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Neoplasias Colorrectales
/
Infecciones por Blastocystis
/
Blastocystis
Tipo de estudio:
Diagnostic_studies
/
Screening_studies
Límite:
Humans
País como asunto:
America do sul
/
Colombia
Idioma:
En
Año:
2023
Tipo del documento:
Article