Sennoside A restrains TRAF6 level to modulate ferroptosis, inflammation and cognitive impairment in aging mice with Alzheimer's Disease.

Li, Xiaojia; Wang, Xiaoping; Huang, Bin; Huang, Rui

Li, Xiaojia; Wang, Xiaoping; Huang, Bin; Huang, Rui.

Li X; Department of Neurology, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Sichuan, 610072, China.
Wang X; Department of Neurology, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Sichuan, 610072, China. Electronic address: wangxiaoping@med.uestc.edu.cn.
Huang B; Department of Neurology, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Sichuan, 610072, China.
Huang R; Department of Neurology, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Sichuan, 610072, China.

Int Immunopharmacol ; 120: 110290, 2023 Jul.

Article en En | MEDLINE | ID: mdl-37216800

Asunto(s)

Enfermedad de Alzheimer; Disfunción Cognitiva; Ferroptosis; Enfermedades Neurodegenerativas; Anciano; Animales; Humanos; Masculino; Ratones; Envejecimiento; Enfermedad de Alzheimer/metabolismo; Péptidos beta-Amiloides/metabolismo; Disfunción Cognitiva/metabolismo; Modelos Animales de Enfermedad; Inflamación; Lipopolisacáridos; Ratones Endogámicos C57BL; Ratones Transgénicos; Senósidos; Factor 6 Asociado a Receptor de TNF/metabolismo

Palabras clave

Alzheimer's Disease; Cognitive impairment; Ferroptosis; Inflammation; Sennoside A; TRAF6

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Enfermedades Neurodegenerativas / Enfermedad de Alzheimer / Disfunción Cognitiva / Ferroptosis Tipo de estudio: Prognostic_studies Límite: Aged / Animals / Humans / Male Idioma: En Año: 2023 Tipo del documento: Article

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