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Polyketide Synthase-Mediated O-Methyloxime Formation in the Biosynthesis of the Oximidine Anticancer Agents.
Vriens, Eveline; De Ruysscher, Dries; Weir, Angus N M; Dekimpe, Sofie; Steurs, Gert; Shemy, Ahmed; Persoons, Leentje; Santos, Ana Rita; Williams, Christopher; Daelemans, Dirk; Crump, Matthew P; Voet, Arnout; De Borggraeve, Wim; Lescrinier, Eveline; Masschelein, Joleen.
  • Vriens E; Laboratory for Biomolecular Discovery and Engineering, Department of Biology, KU Leuven, 3001, Heverlee, Belgium.
  • De Ruysscher D; VIB-KU Leuven Center for Microbiology, 3001, Heverlee, Belgium.
  • Weir ANM; Laboratory for Biomolecular Discovery and Engineering, Department of Biology, KU Leuven, 3001, Heverlee, Belgium.
  • Dekimpe S; VIB-KU Leuven Center for Microbiology, 3001, Heverlee, Belgium.
  • Steurs G; Laboratory for Biomolecular Discovery and Engineering, Department of Biology, KU Leuven, 3001, Heverlee, Belgium.
  • Shemy A; VIB-KU Leuven Center for Microbiology, 3001, Heverlee, Belgium.
  • Persoons L; Laboratory for Biomolecular Discovery and Engineering, Department of Biology, KU Leuven, 3001, Heverlee, Belgium.
  • Santos AR; VIB-KU Leuven Center for Microbiology, 3001, Heverlee, Belgium.
  • Williams C; Department of Chemistry, KU Leuven, 3001, Heverlee, Belgium.
  • Daelemans D; Laboratory for Biomolecular Modelling and Design, Department of Chemistry, KU Leuven, 3001, Heverlee, Belgium.
  • Crump MP; Laboratory of Virology and Chemotherapy, Rega Institute for Medical Research, KU Leuven, 3000, Leuven, Belgium.
  • Voet A; VIB Discovery Sciences, 3001, Heverlee, Belgium.
  • De Borggraeve W; School of Chemistry, University of Bristol, Bristol, BS8 1TS, UK.
  • Lescrinier E; Laboratory of Virology and Chemotherapy, Rega Institute for Medical Research, KU Leuven, 3000, Leuven, Belgium.
  • Masschelein J; School of Chemistry, University of Bristol, Bristol, BS8 1TS, UK.
Angew Chem Int Ed Engl ; 62(34): e202304476, 2023 08 21.
Article en En | MEDLINE | ID: mdl-37218580
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Policétidos / Antineoplásicos Tipo de estudio: Prognostic_studies Idioma: En Año: 2023 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Policétidos / Antineoplásicos Tipo de estudio: Prognostic_studies Idioma: En Año: 2023 Tipo del documento: Article