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Development of a population pharmacokinetic model to characterize the pharmacokinetics of intrathecally administered tominersen in cerebrospinal fluid and plasma.
Yamamoto, Yumi; Sanwald Ducray, Patricia; Björnsson, Marcus; Smart, Kevin; Grimsey, Paul; Vatakuti, Suresh; Portron, Agnes; Massonnet, Benoit; Norris, Daniel A; Silber Baumann, Hanna E.
  • Yamamoto Y; Roche Pharmaceutical Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland.
  • Sanwald Ducray P; Roche Pharmaceutical Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland.
  • Björnsson M; Pharmetheus AB, Uppsala, Sweden.
  • Smart K; Roche Pharmaceutical Research and Early Development, Roche Innovation Center Welwyn, Welwyn Garden City, UK.
  • Grimsey P; Roche Pharmaceutical Research and Early Development, Roche Innovation Center Welwyn, Welwyn Garden City, UK.
  • Vatakuti S; Roche Pharmaceutical Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland.
  • Portron A; Roche Pharmaceutical Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland.
  • Massonnet B; Roche Pharmaceutical Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland.
  • Norris DA; Ionis Pharmaceuticals Inc., Carlsbad, California, USA.
  • Silber Baumann HE; Roche Pharmaceutical Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland.
CPT Pharmacometrics Syst Pharmacol ; 12(9): 1213-1226, 2023 09.
Article en En | MEDLINE | ID: mdl-37221972
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Enfermedad de Huntington Límite: Humans Idioma: En Año: 2023 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Enfermedad de Huntington Límite: Humans Idioma: En Año: 2023 Tipo del documento: Article