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Adenoviral hemorrhagic disease in a farmed elk (Cervus canadensis) in Alberta, Canada.
Domshy, Katrice A; Lung, Oliver; Nebroski, Michelle; Kruczkiewicz, Peter; Ayilara, Ifeoluwa; Woods, Leslie W; Lowe, Evan; Davies, Jennifer L.
  • Domshy KA; Diagnostic Services Unit and Department of Veterinary Clinical and Diagnostic Sciences, University of Calgary Faculty of Veterinary Medicine, 11877 85th Street NW, Calgary, Alberta T3R 1J3 (Domshy, Davies); Canadian Food Inspection Agency, National Centre for Foreign Animal Disease, 1015 Arlington S
  • Lung O; Diagnostic Services Unit and Department of Veterinary Clinical and Diagnostic Sciences, University of Calgary Faculty of Veterinary Medicine, 11877 85th Street NW, Calgary, Alberta T3R 1J3 (Domshy, Davies); Canadian Food Inspection Agency, National Centre for Foreign Animal Disease, 1015 Arlington S
  • Nebroski M; Diagnostic Services Unit and Department of Veterinary Clinical and Diagnostic Sciences, University of Calgary Faculty of Veterinary Medicine, 11877 85th Street NW, Calgary, Alberta T3R 1J3 (Domshy, Davies); Canadian Food Inspection Agency, National Centre for Foreign Animal Disease, 1015 Arlington S
  • Kruczkiewicz P; Diagnostic Services Unit and Department of Veterinary Clinical and Diagnostic Sciences, University of Calgary Faculty of Veterinary Medicine, 11877 85th Street NW, Calgary, Alberta T3R 1J3 (Domshy, Davies); Canadian Food Inspection Agency, National Centre for Foreign Animal Disease, 1015 Arlington S
  • Ayilara I; Diagnostic Services Unit and Department of Veterinary Clinical and Diagnostic Sciences, University of Calgary Faculty of Veterinary Medicine, 11877 85th Street NW, Calgary, Alberta T3R 1J3 (Domshy, Davies); Canadian Food Inspection Agency, National Centre for Foreign Animal Disease, 1015 Arlington S
  • Woods LW; Diagnostic Services Unit and Department of Veterinary Clinical and Diagnostic Sciences, University of Calgary Faculty of Veterinary Medicine, 11877 85th Street NW, Calgary, Alberta T3R 1J3 (Domshy, Davies); Canadian Food Inspection Agency, National Centre for Foreign Animal Disease, 1015 Arlington S
  • Lowe E; Diagnostic Services Unit and Department of Veterinary Clinical and Diagnostic Sciences, University of Calgary Faculty of Veterinary Medicine, 11877 85th Street NW, Calgary, Alberta T3R 1J3 (Domshy, Davies); Canadian Food Inspection Agency, National Centre for Foreign Animal Disease, 1015 Arlington S
  • Davies JL; Diagnostic Services Unit and Department of Veterinary Clinical and Diagnostic Sciences, University of Calgary Faculty of Veterinary Medicine, 11877 85th Street NW, Calgary, Alberta T3R 1J3 (Domshy, Davies); Canadian Food Inspection Agency, National Centre for Foreign Animal Disease, 1015 Arlington S
Can Vet J ; 64(6): 524-528, 2023 06.
Article en En | MEDLINE | ID: mdl-37265810
ABSTRACT
Adenoviral hemorrhagic disease (AHD), caused by deer atadenovirus A (OdAdV-1), affects captive and free-ranging cervids across North America. Here we present a case of AHD in a 6-month-old female elk calf from a farm in Alberta. Histopathology revealed multisystemic vasculitis with endothelial intranuclear inclusion bodies, pulmonary hemorrhage, and small intestinal hemorrhage characteristic of the acute systemic form of AHD. Immunohistochemistry was positive for OdAdV-1, confirming the diagnosis. Whole-genome sequencing of the virus was conducted for phylogenetic comparison. This is the 1st reported case of AHD in a farmed elk in Canada and the 1st reported case in an elk in Alberta. Key clinical message Adenoviral hemorrhagic disease (AHD) is an emerging disease that should be investigated as a top differential when diagnosticians and veterinarians encounter young cervids found dead with pulmonary edema or hemorrhage and/or hemorrhagic enteropathy.
Maladie hémorragique adénovirale chez un wapiti d'élevage (Cervus canadensis) en Alberta, Canada. La maladie hémorragique adénovirale (AHD), causée par l'atadénovirus A du cerf (OdAdV-1), affecte les cervidés en captivité et en liberté partout en Amérique du Nord. Nous présentons ici un cas d'AHD chez un wapiti femelle de 6 mois d'une ferme en Alberta. L'histopathologie a révélé une vascularite multi-systémique avec des corps d'inclusion intranucléaires endothéliaux, une hémorragie pulmonaire et une hémorragie de l'intestin grêle caractéristiques de la forme systémique aiguë de l'AHD. L'immunohistochimie était positive pour OdAdV-1, confirmant le diagnostic. Le séquençage du génome entier du virus a été réalisé à des fins de comparaison phylogénétique. Il s'agit du premier cas signalé d'AHD chez un wapiti d'élevage au Canada et du premier cas signalé chez un wapiti en Alberta.Message clinique cléLa maladie hémorragique adénovirale (AHD) est une maladie émergente qui devrait être investiguée comme un diagnostic différentiel important lorsque les diagnosticiens et les vétérinaires rencontrent de jeunes cervidés trouvés morts avec un œdème pulmonaire ou une hémorragie et/ou une entéropathie hémorragique.(Traduit par Dr Serge Messier).
Asunto(s)

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Ciervos Límite: Animals País como asunto: America do norte Idioma: En Año: 2023 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Ciervos Límite: Animals País como asunto: America do norte Idioma: En Año: 2023 Tipo del documento: Article