Generation of a new Adar1p150 -/- mouse demonstrates isoform-specific roles in embryonic development and adult homeostasis.

Liang, Zhen; Goradia, Ankita; Walkley, Carl R; Heraud-Farlow, Jacki E

Generation of a new Adar1p150 ^-/- mouse demonstrates isoform-specific roles in embryonic development and adult homeostasis.

Liang, Zhen; Goradia, Ankita; Walkley, Carl R; Heraud-Farlow, Jacki E.

Liang Z; St. Vincent's Institute of Medical Research, Fitzroy, Victoria 3065, Australia.
Goradia A; Department of Medicine, Eastern Hill Precinct, Melbourne Medical School, University of Melbourne, Fitzroy, Victoria 3065, Australia.
Walkley CR; St. Vincent's Institute of Medical Research, Fitzroy, Victoria 3065, Australia.
Heraud-Farlow JE; St. Vincent's Institute of Medical Research, Fitzroy, Victoria 3065, Australia cwalkley@svi.edu.au jhfarlow@svi.edu.au.

RNA ; 29(9): 1325-1338, 2023 09.

Article en En | MEDLINE | ID: mdl-37290963

Asunto(s)

Adenosina Desaminasa; ARN Bicatenario; Ratones; Animales; Ratones Noqueados; Adenosina Desaminasa/genética; Adenosina Desaminasa/metabolismo; Homeostasis/genética; Isoformas de Proteínas/genética; Isoformas de Proteínas/metabolismo; Desarrollo Embrionario

Palabras clave

A-to-I RNA editing; ADAR1 isoforms; ADAR1p150; RNA modification; innate immunity; type I interferon

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: ARN Bicatenario / Adenosina Desaminasa Límite: Animals Idioma: En Año: 2023 Tipo del documento: Article

Texto completo

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PubMed Links

Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: ARN Bicatenario / Adenosina Desaminasa Límite: Animals Idioma: En Año: 2023 Tipo del documento: Article